SIF - Società
Italiana di Farmacologia
"SIF - La Ricerca Farmacologica in Italia"
PHARMACOLOGY OF INFLAMATION
AND IMMUNOMODULATION
RESEARCH GROUP MEMBERS:
-
Benoni Giuseppina, R.U.
-
Cuzzolin Laura, T.L.
-
Adami Alessandra, B.
-
Crivellente Federica, D.DR.
AFFILIATION:
Istituto di Farmacologia
Facoltà di Medicina e Chirurgia
Università di Verona
ADDRESS: Policlinico Borgo Roma
CITY: Verona
POSTAL CODE: 37134
TELEPHONE: 45-8098609
FAX: 045-581111
E-MAIL: Laura@Farma.Univr.it
PUBLICATIONS:
-
CONFORTI, A., SCHINELLA, M., BENONI, G., DONINI, M., AND CUZZOLIN, L. Efficacy
and nephrotoxicity of cyclosporin alone and associated to methylprednisolone
in adjuvant arthritis. Int. J. Immunopathol. Pharmacol. 6: 193-198,
1993.
-
BENONI, G., BELLAVITE, P., ADAMI, A., CHIRUMBOLO, S., LIPPI, G., BROCCO,
G., GIULINI, G.M., AND CUZZOLIN, L. Changes in several neutrophil functions
in basketball players before, during and after the sports season. Int.
J. Sport. Med. 16: 34-37, 1995.
-
BENONI, G., BELLAVITE, P., ADAMI, A., CHIRUMBOLO, S., LIPPI, G., BROCCO,
G., AND CUZZOLIN, L. Effect of acute exercise on some haematological parameters
and neutrophil functions in trained and untrained subjects. Eur. J. Appl.
Physiol. 70: 187-191, 1995.
-
BENONI, G., TERZI, M., ADAMI, A., GRIGOLINI, L., DEL SOLDATO, P., AND CUZZOLIN,
L. Plasma concentrations and pharmacokinetic parameters of nitrofenac, using
a simple and sensitive HPLC method. J. Pharmaceut. Sci. 84: 93-95,
1995.
-
MARIOTTO, S., CUZZOLIN, L., ADAMI, A., DEL SOLDATO, P., SUZUKI, H., AND BENONI,
G. Inhibition by sodium nitroprusside of the expression of inducible nitric
oxide synthase in rat neutrophils. Brit. J. Pharmacol. 114: 1105-1106,
1995.
-
MARIOTTO, S., CUZZOLIN, L., ADAMI, A., DEL SOLDATO, P., SUZUKI, H., AND BENONI,
G. Effect of a new non-steroidal antiinflammatory drug, nitroflurbiprofen,
on the expression of inducible nitric oxide synthase in rat neutrophils.
Brit. J. Pharmacol. 115: 225-226, 1995.
-
MARIOTTO, S., MENEGAZZI, M., CARCERERI DE PRATI, A., CUZZOLIN, L., ADAMI,
A., SUZUKI, H., AND BENONI G. Protective effect of NO on gastric lesions
and inhibition of expression of gastric inducible NOS by flurbiprofen and
its nitro-derivative, nitroflurbiprofen. Brit. J. Pharmacol. 116:
1713-1714, 1995.
-
MINUZ, P., LECHI, C., TOMMASOLI, R., GAINO, S., DEGAN, M., ZULIANI, V., BONAPACE,
S., BENONI, G., ADAMI, A., CUZZOLIN, L., AND LECHI, A. Antiaggregating and
vasodilatory effects of a new nitroderivative of acetylsalicylic acid.
Thromb. Res. 80: 367-376, 1995.
-
CUZZOLIN, L., ADAMI, A., DEGAN, M., CRIVELLENTE, F., BONAPACE, S., MINUZ,
P., AND BENONI, G. Effect of single and repeated doses of a new nitroderivative
of acetylsalicylic acid on platelet TXA2 production in rats. Life
Sci. 58: 207-210, 1996.
RESEARCH GROUP MEMBERS:
-
Bruni Alessandro, P.O.
-
Cusinato Federico T.L.
-
Carrara Marisa T.L.
AFFILIATION:
Dipartimento di Farmacologia "E. Meneghetti"
Facoltà di Medicina e Chirurgia
Università di Padova
ADDRESS: Largo E. Meneghetti, 2
CITY: Padova
POSTAL CODE: 35131
TELEPHONE: 049 8275081
FAX: 049 8275093
PUBLICATIONS:
-
VIOLA G., MIETTO L., SECCHI F.E., PING L. AND BRUNI A. Absorption and
distribution of arachidonate in rats receiving lysophospholipids by oral
route. J. Lipid Res. 34: 1843-1851, 1993.
-
SANTAMBROGIO L., LIPARTITI M., BRUNI A. AND DAL TOSO R. Dopamine receptors
on human T and B lymphocytes. Neuroimmunol., 45: 113-120, 1993.
-
BELLINI F. AND BRUNI A. Role of a serum phospholipase A1 in the
phosphatidylserine-induced T cell inhibition. FEBS Lett. 316: 1-4,
1993.
-
MONASTRA G., CROSS A.H., BRUNI A. AND RAINE C.S. Phosphatidylserine, a putative
inhibitor of tumor necrosis factor, prevents autoimmune demyelination.
Neurology 43: 153-163, 1993.
-
BRUNI A., MIETTO L., SECCHI F.E. AND CHIZZOLINI C. Lipid mediators of immune
reactions: effect of a linked phosphorylserine group. Immunol. Lett.
42: 87-90, 1994.
-
BRUNI A., MIETTO L., SECCHI F.E., PONZIN D., MONASTRA G., KIRSCHNER G., CUSINATO
F. AND CHIZZOLINI C. Inhibition by cholesterylphosphorylserine of T cell-mediated
immune responses in mice. Int. J. Immunopharmacol. 17: 517-521, 1995.
RESEARCH GROUP MEMBERS:
-
Caprino Luciano, P.O.
-
Togna Giuseppina Ines, P.A.
-
Togna Anna Rita, T.L.
-
Graziani Manuela, T.L.
-
Russo Pierluigi, B
AFFILIATION:
Istituto di Farmacologia Medica (IV Cattedra)
Facoltà di Medicina e Chirurgia
Università "La Sapienza"
ADDRESS: P.le Aldo Moro, 5
CITY: Roma
POSTAL CODE: 00185
TELEPHONE: 06-4991/2920, 2905
FAX: 06-4991/2393
PUBLICATIONS:
-
CAPRINO L., AND TOGNA G. The problems of the safety evaluation of biotechnology
derived drugs. Biomed. Environ. Sci. 6: 413-418, 1993.
-
CIABATTONI G., MONTUSCHI P., CURRO' D., TOGNA G., PREZIOSI P. Effects
of VIP on antigen-induced bronchoconstriction and thromboxane release in
guinea-pig lung. Brit. J. Pharmacol. 109: 243-250, 1993.
-
CAPRINO L., TOGNA A.R., STELLA C., TOGNA G. An in vitro method for evaluating
vascular endothelial ADPase activity. J. Pharmacol. Toxicolog. Met.
35: 153-157, 1996.
-
TOGNA G., GRAZIANI M., SORRENTINO C., CAPRINO L. Prostanoid production in
in the presence of platelet activation in hypoxic cocaine-treated rats.
Haemostasis, 26 : In press, 1996.
RESEARCH GROUP MEMBERS:
-
Di Rosa Massimo, P.O.
-
Carnuccio Rosa, P.A.
-
Sautebin Lidia, R.U.
-
Ialenti Armando, R.U.
-
Iuvone Teresa, R.U.
-
Ianaro Angela, B.PDR.
-
Rombolà Laura, D.DR.
AFFILIATION:
Dipartimento di Farmacologia Sperimentale
Facoltà di Farmacia
Università di Napoli Federico II
ADDRESS: Via Domenico Montesano, 49
CITY: Napoli
POSTAL CODE: 80131
TELEPHONE: 081-7486-414, 422
FAX: 081-7486-403
PUBLICATIONS:
-
IALENTI, A., MONCADA, S., AND DI ROSA M. Modulation of adjuvant arthritis
by endogenous nitric oxide. Brit. J. Pharmacol. 101: 701-706, 1993.
-
IUVONE, T., CARNUCCIO, R., AND DI ROSA, M. Characterization of vasocortin-like
proteins induced by dexamethasone in endothelial cells. Eur. J.
Pharmacol. 243: 163-167, 1993.
-
IANARO, A., O'DONNELL, C.A., DI ROSA, M., AND LIEW, F.Y. A nitric oxide synthase
inhibitor reduces inflammation, down-regulates inflammatory cytokines and
enhances interleukin-10 production in carrageenin-induced oedema in mice.
Immunology. 82: 370-375, 1994.
-
SAUTEBIN, L., AND DI ROSA, M. Nitric oxide modulates prostacyclin biosynthesis
in the lung of endotoxin-treated rats. Eur. J. Pharmacol. 264: 193-196,
1994.
-
IUVONE, T., CARNUCCIO, R., AND DI ROSA, M. Modulation of granuloma formation
by endogenous nitric oxide. Eur. J. Pharmacol. 265: 89-92, 1994.
-
IANARO, A., O'DONNELL, C.A., DI ROSA, M. AND LIEW, F.Y. Expression of TGF-
in attenuated Salmonella tiphimurium: oral administration leads to
the reduction of inflammation, IL-2 and INF-, but enhancement of IL-10, in
carrageenin oedema in mice. Immunology. 84: 8-15, 1995.
-
SAUTEBIN, L., IALENTI, A., IANARO, A., AND DI ROSA, M. Modulation by nitric
oxide of prostaglandin biosynthesis in the rat. Brit. J. Pharmacol.
114: 323-328, 1995.
-
SAUTEBIN, L., IALENTI, A., IANARO, A., AND DI ROSA, M. Endogenous nitric
oxide increase prostaglandin biosynthesis in carrageenin rat paw oedema.
Eur. J. Pharmacol. 286: 219-222, 1995.
-
DI ROSA, M., IALENTI, A., IANARO, A., AND SAUTEBIN, L. Interaction between
nitric oxide and cyclooxygenase pathways. Prostagland. Leuk. Essent. Fatty
54: 229-238, 1996.
-
IUVONE, T., D'ACQUISTO, F., CARNUCCIO, R., AND DI ROSA, M. Nitric oxide inhibits
LPS-induced tumor necrosis factor synthesis in vitro and in vivo. Life
Sci. 59: PL207-PL211, 1996.
RESEARCH GROUP MEMBERS:
-
Fantozzi Roberto, P.O.
-
Cassone Chiara, P.A.
-
Dianzani Chiara, R.U.
-
Lombardi Grazia, R.U.
-
Ferrara Cinzia, D.DR.
-
Pisterna Alessia, B.
AFFILIATION:
Sezione di Farmacologia-Dipartimento di Anatomia, Farmacologia e Medicina
Legale
Facoltà di Farmacia
Università degli Studi di Torino
ADDRESSES:
Turin: Via Pietro Giuria, 9
CITY: Torino
POSTAL CODE: 10126
TELEPHONE: 011-670-7688-7689
FAX: 011-670-7688
Novara: Viale F. Ferrucci, 35
CITY: Novara
POSTAL CODE: 28100
TELEPHONE: 0321-629028
FAX: 0321-611043
PUBLICATIONS:
-
BRUNI, F., COSTANZO, A., SELLERI, S., GUERRINI, G., FANTOZZI, R., PIRISINO,
R., BRUNELLESCHI, S. Synthesis and study of the anti-inflammatory properties
of some pyrazolo [1,5-]pyrimidine derivatives. J. Pharmaceut. Sci.
82: 480-486, 1993.
-
LOMBARDI, G., SZEKELY, A.M., BRISTOL, L.A., GUIDOTTI, A., MANEV, H. Induction
onithine decarboxylase by N-methyl-D-aspartate receptor activation is unrelated
to potentiation of glutamate excitotoxicity by polyamines in cerebellar granule
neurons. J. Neurochem. 60: 1317-1324, 1993.
-
CASSONE, M.C., LOMBARD, A., ROSSETTI, V., URCIUOLI, R., ROLFO, M. Effect
of in vivo He-Ne laser irradiation on biogenic amine levels in rat brain.
J. Photochem. Photobiol. B: Biology. 18: 291-294, 1993.
-
DIANZANI, C., BRUNELLESCHI, S., VIANO, I., FANTOZZI, R. Adenosine modulation
of primed human neutrophils. Eur. J. Pharmacol. 263: 223-226, 1994.
-
MIAN, M., BENETTI, D., ALOISI, R., ROSINI, S., FANTOZZI, R. Effects of
bisphosphonate derivatives on macrophage function. Pharmacology. 49:
336-342, 1994.
-
SILVESTRO, L., VIANO, I., MACARIO, M., COLANGELO, D., MONTRUCCHIO, G., PANICO,
S., FANTOZZI, R. Effects of heparin and its desulfated derivatives on
leukocytes-endothelial adhesion. Seminars Thromb. Hemostasis. 20:
254-258, 1994.
-
BRUNELLESCHI, S., GUIDOTTO, S., TONSO, E., VIANO, I., FANTOZZI, R. Modulation
by protein kinase C of enhanced responsiveness to tachykinins in
ovalbumin-sensitized guinea pig alveolar macrophages. Neuropeptides.
30: 249-260, 1996.
-
DIANZANI, C., PARRINI, M., FERRARA, C., FANTOZZI, R. Effect of 4-hydroxynonenal
on superoxide anion production from primed human neutrophils. Cell Biochem
Funct. 14: In press, 1996.
RESEARCH GROUP MEMBERS :
-
Fioretti Maria Cristina, P.O.
-
Contessa Anna Rita, P.O.
-
Pucetti Paolo, P.O.
-
Allegrucci Massimo, R.U.
-
Campanile Franca, R.U.
-
Giampietri Antonio, R.U.
-
Grohmann Ursula, R.U.
-
Bianchi Roberta, T.L.
-
Belladonna Maria Laura, D.D.R.
-
Fallarino Francesca, D.D.R.
-
Silla Silvia, D.D.R.
AFFILIATION :
Sezione di Farmacologia
Dipartimento di Medicina Sperimentale e Scienze Biochimiche
Facoltà di Farmacia
Università di Perugia
ADDRESS: Via del Giochetto
CITY: Perugia
POSTAL CODE: 06100
TELEPHONE: 075/585 3472-96-63
FAX : 075/585-3473
PUBLICATIONS :
-
CAMPANILE F., GIAMPIETRI A., GROHMANN U., BINAGLIA L., FIORETTI M.C., AND
PUCCETTI P. Accelerated hematopoietic recovery and protective effect of the
cyclooxygenase inhibitor indomethacin in bacterial infection of neutropenic
mice. Cell. Immunol. 147 : 341-352, 1993.
-
GROHMANN U., BINAGLIA L., PUCCETTI P., AND FIORETTI M.C. Cell-mediated immunity
to chemically xenogenized tumors-VI. The effect of cell treatment with retroviral
env antisense oligonucleotides. Int. J. Immunopharmac. 15 :
567-572, 1993.
-
GROHMANN U., FIORETTI M.C., BINAGLIA L., BELLADONNA M.L., BIANCHI R., AND
PUCCETTI P. Immunogenic properties of retroviral protein P15E from drug-treated
murine mastocytoma P815. Int. J. Cancer 55 : 344-350, 1993.
-
PUCCETTI P., BIANCHI R., FIORETTI M.C., AYROLDI E., UYTTENHOVE C., VAN PEL
A., BOON T., AND GROHMANN U. Use of a skin test assay to determine
tumor-specificCD8+T cell reactivity. Eur. J. Immunol.
24 : 1446-1452, 1994.
-
GROHMANN U., BELLADONNA M.L., ALLEGRUCCI M., SILLA S., SCHIAFFELLA E., FIORETTI
M.C., AND PUCCETTI P. Endogenous retroviral gp70 genes of the murine lymphoma
L5178Y : analysis of restriction fragment polymorphism upon induction
of drug-mediated immunogenicity. Viral Immunol. 7 :155-167,
1994.
-
GROHMANN U., PUCCETTI P., BELLADONNA M.L., FALLARINO F., BIANCHI R., BINAGLIA
L., SAGAKUCHI K., MAGE M.G., APPELLA E., AND FIORETTI M.C. Multiple point
mutations in an endogenous retroviral gene confer high immunogenicity on
a drug-treated murine tumor. J. Immunol. 154 : 4630-4641, 1995.
-
GROHMANN U., BIANCHI R., FIORETTI M.C., FALLARINO F., BINAGLIA L., UYTTENHOVE
C., VAN PEL A., BOON T., AND PUCCETTI P. CD8+ cell activation
to a MAjor mastocytoma rejection antigen, P815AB : requirement for tumor
helper peptides in priming for skin test reactivity to a P815AB-related
peptide. Eur. J. Immunol. 25 : 2797-2802, 1995.
-
CAMPANILE F., GIAMPIETRI A., GROHMANN U., BELLADONNA M.L., FIORETTI M.C.,
AND PUCCETTI P. Evidence for tumor necrosis factor asa mediator of the toxocity
of a cyclooxygenase inhibitor in Gram-negative sepsy. Eur. J. Pharmacol.
307 : 191-199, 1996.
-
BIANCHI R., GROHMANN U., BELLADONNA M.L.,SILLA S., FALLARINO F., AYROLDI
E., FIORETTI M.C., AND PUCCETTI P. IL-12 is both required and sufficient
for initiating T cell reactivity to a class I-restricted tumor peptide (P815AB)
following transfer of P815AB-pulsed dendritic cells. J. Immunol.
157 : 1589-1597, 1996.
RESEARCH GROUP MEMBERS :
-
Geppetti Pierangelo, R.U.
-
Emanueli Costanza, D.DR.
-
Figini Michela, D.DR.
AFFILIATION:
Sezione di Farmacologia, Dipartimento di Medicina Clinica e Sperimentale
Facoltà di Medicina e Chirurgia
Università di Ferrara
ADDRESS: Via Fossato di Mortara 19
CITY: Ferrara
POSTAL CODE: 40100
TELEPHONE: (0532) 291-226
FAX: (0532) 291-205
E-MAIL: gpp@ifeuniv.unife,it
PUBLICATIONS :
-
BERTRAND C, NADEL JA, YAMAWAKI I, GEPPETTI P. Role of kinins in the vascular
extravasation evoked by antigen and mediated by tachykinins in guinea pig
trachea. J. Immunol., 151:4902-4907,1993.
-
HUBER O, BERTRAND C, BUNNETT NW, PELLEGRINI CA, DEBAS HT, NADEL JA, GEPPETTI
P. Tachykinins contract the circular muscle of the human esophageal body
in vitro via NK2 receptors. Gastroenterology, 105:981-987, 1993.
-
BEVAN S, GEPPETTI P. Protons, small stimulants of capsaicin-sensitive sensory
nerves. Trends Neurosci., 17:509-512, 1994.
-
FAHY JV, WONG HH, GEPPETTI P, REIS JM, HARRIS SC, MACLEAN DB, NADEL JA, BOUSHEY
HA. Effect of an NK-1 receptor antagonist (CP-99,994) on hypertonic
saline-induced bronchoconstriction and cough in male asthmatic subjects.
Amer. J. Respir. Crit. Care Med.152:879-884, 1995.
-
FUSCO BM, MARABINI S, MAGGI CA, GEPPETTI P. Preventive effect of repeated
nasal applications of capsaicin in cluster headache. Pain, 59:321-325,
1995.
-
FIGINI M, RICCIARDOLO FLM, JAVDAN P, NJIKAMP FP, EMANUELI C, PRADELLES P,
FOLKERTS G, GEPPETTI P. Evidence that epithelium-derived relaxing factor
released by bradykinin in the guinea pig trachea is nitric oxide. Amer.
J. Respir. Crit. Care Med. 153:918-923, 1996.
-
RICCIARDOLO FLM, GEPPETTI P, MISTRETTA A, NADEL JA, BELLOFIORE S, SAPIENZA
MA, DI MARIA GU. Inhibition of nitric oxide biosynthesis potentiates
bradykinin-induced bronchoconstriction in asthmatics. Lancet 348:374-377,
1996.
-
FIGINI M, EMANUELI C, BETRAND C, JAVDAN P, GEPPETTI P. Evidence that tachykinins
relax the guinea-pig trachea via nitric oxide release and by stimulation
of a septide-insensitive NK1 receptor. Brit. J. Pharmacol. 117:1270-1276,
1996.
-
ROSENECKER J, HONG K, ZHANG W, LAUSIER J, GEPPETTI P, YOSHIHARA S,
PAPAHADJOPUOLOS D, NADEL JA. Increased liposome extravasation in selected
tissues: effect of substance P. Proc. Nat. Acad. Sci. USA 93:7236-7241,
1996.
-
BERTRAND C, GEPPETTI P. Tachykinin and kinin receptor antagonists: therapeutic
perspectives in allergic airway disease. Trends Pharmacol. Sci.,
17:255-259, 1996.
RESEARCH GROUP MEMBERS:
-
Parente Luca, P.O. (1)
-
Biondi Filippo, R.U.
-
Vetri Piera, R.U.
-
Perretti Mauro, R.I.
-
Solito Egle, R.I.
AFFILIATION:
Istituto di Farmacologia e Farmacognosia
Facoltà di Farmacia
Università di Palermo
ADDRESS: Via Forlanini, 1
CITY: Palermo
POSTAL CODE: 90134
TELEPHONE: 091-651-2262, 2425
FAX: 091-6512469
E-MAIL: l.parente@mbox.netway.it
PUBLICATIONS:
-
PALLA, G. BENSI, E. SOLITO, D. TORNESE BUONAMASSA, G. FASSINA, G. RAUGEI,
F. SPANO, C. GALEOTTI, M. MORA, M. DOMENIGHINI, M. ROSSINI, E. GALLO, V.
CARINCI, M. BUGNOLI, F. BERTINI, L. PARENTE, M. Melli, Loop substitution
as a tool to identify active sites of interleukin1 . J. Biol.
Chem. 268: 13486-13492, 1993.
-
DE CATERINA, R. SICARI, D. GIANNESSI, P.L. PAGGIARO, P. PAOLETTI, G. LAZZERINI,
W. BERNINI, E. SOLITO, L. PARENTE, Macrophage-specific eicosanoid synthesis
inhibition and lipocortin-1 induction by glucocorticoids. J. Appl.
Physiol. 75: 2368-2375, 1993.
-
SOLITO, S. NUTI, L. PARENTE, Dexamethasone induces the translocation of
lipocortin (annexin) 1 to the cell membrane of U-937 cells. Brit. J.
Pharmacol. 112: 347-348, 1994.
-
PALMI, M. FROSINI, C. BECHERUCCI, G.P. SGARAGLI, L. PARENTE, Increase of
extracellular brain calcium is involved in interleukin-1 -induced pyresis
in the rabbit; antagonism by dexamethasone. Brit. J. Pharmacol. 112:
449-452, 1994.
-
GO, F. ZUIDERVEN, L. DE LEY, J.G. TER HAAR, L. PARENTE, E. SOLITO, W.M. MOLENAAR,
Effects of steroids on brain lipocortin immunoreactivity. Acta
Neurochir. 60: 101-103, 1994.
-
PARENTE, E. SOLITO, Association between glucocorticoids and lipocortin-1.
Trends Pharmacol. Sci. 15: 362, 1994.
-
MIRTELLA, G. POZZOLI, G. GUERRIERO, P. GHIARA, L. PARENTE, P. PREZIOSI, P.
NAVARRA, Evidence that the interleukin-1 -induced prostaglandin E2 release
from rat hypothalamus is mediated by type I and type II interleukin-1 receptors.
J. Neuroimmunol. 61: 171-177, 1995.
-
AMBROSETTI, E. PALLA, A. MIRTELLA, C. GALEOTTI, E. SOLITO, P. NAVARRA, L.
PARENTE, M. MELLI, Synthetic alleles at position 121 define a functional
domain of human interleukin-1 . Eur. J. Biochem. 238: 308-316, 1996.
-
MONTUSCHI, G. TRINGALI, A. MIRTELLA, L. PARENTE, E. RAGAZZONI, P. PREZIOSI,
P. NAVARRA, Interleukin-1 release from rat gastric fundus. Amer. J.
Physiol. 271: G275-G281,1996.
-
CIFONE, L. CIRONI, P. RONCAIOLI, S. MARTINOTTI, E. TONIATO, L. CILENTI, D.
BOTTI, E. SOLITO, L. PARENTE, A. SANTONI Phospholipase A2 activity and calpactin
I levels in rat lymphokine-activated killer cells: correlation with the cytotoxic
activity. Cell. Immunol. 170: 274-282, 1996.
RESEARCH GROUP MEMBERS:
-
Patrono Carlo, P.O.
-
Patrignani Paola, T.L.
-
Panara Maria Rosaria, DDR
-
Santini Giovanna, B.
-
Sciulli Maria Gina, B
-
Padovano Roberto, B.
AFFILIATION:
Cattedra di Farmacologia I, Istituto di Fisiopatologia Medica
Facoltà di Medicina e Chirurgia
Università di Chieti "G. D'Annunzio"
ADDRESS: Via dei Vestini, 31
CITY: Chieti
POSTAL CODE: 66013
TELEPHONE: 0871-355-775, 701, 772, 773, 748
FAX: 0871-355-718
E-MAIL: ppatrignani@unich.it
PUBLICATIONS:
-
CIABATTONI, G., SHAHROM UJANG, SRITARA, P., ANDREOTTI, F., DAVIES, G., SIMONETTI,
B.M., PATRONO, C., AND MASERI, A. Aspirin, but not heparin, suppresses the
transient increase in thromboxane biosynthesis associated with cardiac
catheterisation or coronary angioplasty. J. Amer. Coll. Cardiol.,
21:1377-1382, 1993.
-
FABBRINI, M.S., VITALE, A., PEDRAZZINI, E., NITTI, G., ZAMAI, M., TAMBURIN,
M., CAIOLFA, V.R., PATRONO, C., AND BENATTI, L. In vivo expression of mutant
preproendothelins: hierarchy of processing events but no strict requirement
of Trp-Val at the processing site. Proc. Nat. Acad. Sci. USA,
90:3923-3928, 1993.
-
DE FERRARI, G..M, SALVATI, P., GROSSONI,. M, UKMAR, G., VAGA, L., PATRONO,
C., AND SCHWARTZ, P.J. Pharmacologic modulation of the autonomic nervous
system in the prevention of sudden cardiac death. A study with propranolol,
methacoline and oxotremorine in conscious dogs with a healed myocardial
infarction. J. Amer. Coll. Cardiol., 21:283-288,1993.
-
DI MINNO, G., DAVI', G., MARGAGLIONE, M., CIRILLO, F., GRANDONE, E.,
CIABATTONI, G., CATALANO, I., STRISCIUGLIO, P., ANDRIA, G., PATRONO, C.,
AND MANCINI, M. Abnormally high thromboxane A2 biosynthesis in
homozygous homocystinuria. Evidence for platelet involvement and
probucol-sensitive mechanism. J. Clin. Invest., 92:1400-1405,1993.
-
DAVI', G., PATRONO, C., CATALANO, I., CUSTRO, N., GIAMMARRESI, C.,
GANCI, A., COSENTINO, F., AND NOTARBARTOLO, A. Inhibition of thromboxane
biosynthesis and platelet function by indobufen in type II diabetes
mellitus. Arterioscler. Thromb., 13:1346-1351, 1993.
-
PATRONO, C. Aspirin as an antiplatelet drug. N. Engl. J. Med., 330:
1287-1292, 1994.
-
NOTARBARTOLO, A., DAVI', G., AVERNA, M., BARBAGALLO, M.B., GANCI, A.,
GIAMMARRESI, C., LA PLACA, F.P., AND PATRONO, C. Inhibition of thromboxane
biosynthesis and platelet function by simvastatin in type IIa
hypercholesterolemia. Arterioscler. Thromb., 15:247-252, 1995.
-
BARBUI, T., DE GAETANO, G., FINAZZI, G., LANDOLFI, R., MARCHIOLI, R., PATRONO,
C., TOGNONI, G., AND THE GRUPPO ITALIANO STUDIO POLICITEMIA (GISP). Polycythemia
Vera: the natural history of 1213 patients followed for 20 years. Ann.
Intern. Med., 123:656-661, 1995.
-
PANARA, M.R., GRECO, A., SANTINI, G., SCIULLI, M.G., ROTONDO, M.T., PADOVANO,
R., DI GIAMBERARDINO, M., CIPOLLONE, F., CUCCURULLO, F., PATRONO, C., AND
PATRIGNANI, P. Effects of the novel antiinflammatory compounds NS-398 and
L-745,337 on the cyclooxygenase activity of human blood prostaglandin
endoperoxide synthases. Brit. J. Pharmacol., 116:2429-2434, 1995.
-
PATRIGNANI, P., SANTINI, G., PANARA, M.R., SCIULLI, M.G., GRECO, A., ROTONDO,
M.T., DI GIAMBERARDINO, M., MACLOUF, J., CIABATTONI, G., AND PATRONO, C.
Induction of prostaglandin endoperoxide synthase-2 in human monocytes is
associated with cyclooxygenase-dependent F2-isoprostane
formation. Brit. J. Pharmacol., 118:1285-1293, 1996.
RESEARCH GROUP MEMBERS :
-
Pinto Aldo, P.A.
-
Autore Giuseppina, R.U.
-
Capasso Anna, R.U.
AFFILIATION :
Sezione di Farmacologia
Dipartimento di Scienze Farmaceutiche
Facoltà di Farmacia
ADDRESS: Piazza Vittorio Emanuele 9
CITY: Penta, Salerno
POSTAL CODE: 84084
TELEPHONE: 089/968950-968909-988916
FAX: 089/968937
PUBLICATIONS:
-
SORRENTINO, L. SORRENTINO AND A. PINTO Effect of some products of protein
catabolism on endothelium-dependent and independent relaxation of rabbit
thoracic aorta rings. J. Pharmacol. Exp. Ther. 266 : 626-633,
1993.
-
CAPASSO, N. MASCOLO, A.A. IZZO, G. AUTORE, G. DI CARLO Effect of Senna is
not mediated by platelet activating factor. Pharmacology, 47 :58-63,
1993.
-
MASCOLO, A.A. IZZO, G. AUTORE, F. BARBATO, F. CAPASSO Nitric oxide and castor
oil induced diarrhoea. J. Pharmacol. Exper. Ther. 68 : 291-295,
1994.
-
CAPASSO, L. SORRENTINO, A. DI GIANNUARIO, S. PIERETTI, A. LOIZZO
Des-tyrosine-g-endorphin effect on neocortical spike and wave spindling in
DBA/2J mice. Eur. J. Pharmacol. 261 : 209-212, 1994.
-
LOIZZO, S. PIERETTI, A. DI GIANNUARIO, M.R. DOMENICI, S. SAGRATELLA, A. CAPASSO,
L. SORRENTINO The synthetic glucocorticoid dexamethasone induces selective
inhibition of the central m opioid receptor: functional in vivo and in vitro
evidence in rodents. Brit. J. Pharmacol. 113 : 1416-1422, 1994.
-
MASCOLO, A.A. IZZO, G. AUTORE, F.M. MAIELLO, F. CAPASSO Acetic acid induced
colitis in normal and essential fatty acid deficient rats. J. Pharmacol.
Exp. Ther. 272 : 469-475, 1995.
-
R. SORRENTINO AND A. PINTO Effect of methylguanidine on rat bood pressure:
role of endothelial nitric oxide synthase. Brit. J. Pharmacol. 115 :
510-514, 1995.
-
IUVONE, A. CAPASSO, F. D'ACQUISTO, R. CARNUCCIO Opioids inhibit the induction
of nitric oxide synthase in J774 macrophages. Biochem. Bioph. Res. Comm.
212 : 975-980, 1995.
-
CIRINO, R. SORRENTINO, C. CICALA, L. SORRENTINO AND A. PINTO Indimetacin
and thrombossane A2/Prostaglandin H2 antagonist SQ29,548, impair in vitro
contractions of aortic rings of ex vivo-treated lipopolysaccharide rats.
J. Lipid Mediator Cell Signal. 13 : 177-187, 1996.
-
CAPASSO, A. DI GIANNUARIO, A. LOIZZO, S. PIERETTI, S. SAGRATELLA AND L.
SORRENTINO Dexamethasone selective inhibition of opioid acute physical dependence
in isolated tissues. J. Pharmacol. Exp. Ther. 276 : 743-751,
1996.
RESEARCH GROUP MEMBERS:
-
Pinza Mario, Dir. R.
-
Prosdocimi Marco, C.P.E.
-
Campana Alberto, C.L.
-
Marchetti Marcello, C.L.
-
Milanese Claudio, C.L.
-
Rossi Vilma, C.L.
-
Capezzone de Joannon Alessandra, R.I.
-
Coletta Isabella, R.I.
-
D'Onofrio Eutimio, R.I.
-
Guglielmotti Angelo, R.I.
-
Jovicevic Ljuba, R.I.
-
Mangano Giorgina, R.I.
-
Martinelli Biancangela, R.I.
-
Panei Marina, R.I.
-
Soldo Lucia, R.I.
AFFILIATION:
Angelini Ricerche S.p.A.
ADDRESS: P.le della Stazione snc
CITY: S. Palomba - Pomezia (Rm)
POSTAL CODE: 00040
TELEPHONE: 06 - 910451
FAX: 06 - 91984597
PUBLICATIONS:
-
GUGLIELMOTTI, A., SILVESTRINI, B., SASO, L., ZWAIN, I. AND CHENG, C.Y. Chronic
inflammatory response in the rat can be blocked by bindarit. Biochem.
Mol. Biol. Int. 29: 747-756, 1993.
-
SASO, L., SILVESTRINI, B., GUGLIELMOTTI, A., LAHITA, R. AND CHENG, C.Y. Abnormal
glycosilation of alpha 2-macroglobulin, a non-acute-phase protein, in patients
with autoimmune diseases. Inflammation. 17: 465-479, 1993.
-
PERI, G., MILANESE, C., MATTEUCCI, C., RUCO, L., DAN, Z., SOZZANI, S., COLETTA,
I. AND MANTOVANI, A. A new monoclonal antibody (5D3-F7) which recognizes
human monocyte-chemiotactic protein-1 but not related chemokines. Development
of a sandwich ELISA and in situ detection of producing cells. J. Immun.
Meth. 174: 249-257, 1994.
-
WOODWARD, R.M., POLENZANI, L. AND MILEDI, R. Effects of fenamates and other
non-steroidal anti-inflammatory drugs on rat brain GABA A receptors expressed
in Xenopous oocytes. J. Pharmacol.Exp. Ther. 268: 806-817, 1994.
-
GUGLIELMOTTI, A., CAPEZZONE DE JOANNON, A., CAZZOLLA, N., MARCHETTI, M.,
SOLDO, L., CAVALLO, G. AND PINZA, M. Radical scavenger activity of bendazac,
an anticataract non-steroidal antiinflammatory agent. Pharmacol. Res.
32: 369-373, 1995.
-
MILEO A.M., PALMA E., POLENZANI L., LIMATOLA C., GRASSI F. AND EUSEBI F.
Protein kinases C modulates exogenous acetylcholine receptors currents in
Xenopus oocytes. J.Neurosci.Res. 41: 443-451 1995.
-
CAPEZZONE, A., MANGANO, G., PERI, G., ROSSI, V. AND MILANESE, C. A
flow-cytometric method to evaluate drug anti-aggregating effect on
polymorphonuclear cells. J.Pharmacol. Toxicol. Met. 36: 21-28, 1996.
-
DELPINO A., MILEO A.M., LAPENTA V., PISELLI P., VERDINA A. AND POLENZANI
L. Characterization of a new high temperature-induced mammalian heat shock
protein (HSP 66), antigenically related to heat shock protein 72.
J.Cell.Biochem. 63: 51-60 1996.
-
SIRONI, M., POZZI, P., POLENTARUTTI, N., BENIGNI, F., COLETTA, I., GUGLIELMOTTI,
A., MILANESE, C., GHEZZI, P., VECCHI, A., PINZA, M. AND MANTOVANI, A. Inhibition
of inflammatory cytokine production and protection against septic shock by
benzydamine. Cytokine. In press, 1996.
RESEARCH GROUP MEMBERS:
-
Regoli Domenico, P.O.
-
Calò Girolamo, R.U.
-
Rizzi Anna, D. DR.
-
Bogoni Giovanni, D. DR.
AFFILIATION:
Istituto di Farmacologia
Università di Ferrara.
ADDRESS: Via Fossato di Mortara, 17-19
CITY: Ferrara
POSTAL CODE: 44100
TELEPHONE: 0532-291203
FAX: 0532-291205
E-MAIL: fmc@ifeuniv.unife.it
PUBLICATIONS:
-
LOPES P., KAR S., TOUSIGNANT C., REGOLI D., QUIRION R., AND COUTURE R.
Autoradiographic localization of [125I-Tyr8]-bradykinin receptor binding
sites in the guinea pig spinal cord. Synapse 15:48-57 1993.
-
BASCANDS J.L., PECHER C., ROUAUD S., EMOND C., TACK J.L., BASTIE M.J., BURCH
R., REGOLI D., AND GIROLAMI J.P. Evidence for existence of two distinct
bradykinin receptors on rat mesangial cells. Amer. J. Physiol.,
264:0002-9513 1993.
-
CHAHINE R., ADAM A., YAMAGUCHI N., GASPO R., REGOLI D., AND NADEAU R.. Protective
effects of bradykinin on the ischaemic heart: implication of the B1
receptor. Brit. J. Pharmacol. 108:318-22 1993.
-
PICARD P., BOUCHER S., REGOLI D., GITTER B.D., HOWBERT J.J., AND COUTURE
R. Use of non-peptide tachykinin receptor antagonists to substantiate the
involvement of NK1 and NK2 receptors in a spinal nociceptive reflex in the
rat. Eur .J. Pharmacol. 232:255-61 1993.
-
RIBUOT C., GODIN D., COUTURE R., REGOLI D., AND NADEAU R. In vivo
B2-receptor-mediated negative chronotropic effect of bradykinin in canine
sinus node. Amer. J. Physiol. 265:0002-9513 1993.
-
REGOLI D., BOUDON A., AND FAUCHERE J.L.. Receptors and antagonists for substance
P and related peptides. Pharmacol. Rev. 46:551-99 1994.
-
REGOLI D., GOBEIL F., NGUYEN Q.T., JUKIC D., SEOANE P.R., SALVINO J.M., AND
SAWUTZ D.G.. Bradykinin receptor types and B2 subtypes. Life Sci.
55:735-49 1994.
-
PICARD P., REGOLI D., AND COUTURE R. Cardiovascular and behavioural effects
of centrally administered tachykinins in the rat: characterization of receptors
with selective antagonists. Brit. J. Pharmacol. 112:240-9 1994.
-
CROWTHER R., JUKIC D., REGOLI D., AND RANGACHARI P.K. Functional subtyping
of neurokinin receptors on canine proximal colonic mucosa. J. Pharmacol.
Exp. Ther. 268:1374-80 1994.
-
BERTHIAUME N., CLAING A., REGOLI D., WARNER T.D., AND D'ORLEANS-JUSTE P.
Characterization of receptors for kinins and neurokinins in the arterial
and venous mesenteric vasculatures of the guinea-pig. Brit. J.
Pharmacol. 115:1319-25 1995.
RESEARCH GROUP MEMBERS:
-
Riccardi Carlo, P.O.
-
Delfino Domenico, R.U.
-
Ronchetti Simona, D.DR.
-
Migliorati Graziella, T.L.
-
Ayroldi Emira, T.L.
-
D'Adamio Francesca, T.L.
AFFILIATION:
Sezione di Farmacologia, Tossicologia e Chemioterapia
Dipartimento di Medicina Clinica, Patologia e Farmacologia
Facoltà di Medicina e Chirurgia
Università degli Studi di Perugia
ADDRESS: Via del Giochetto
CITY: Perugia
POSTAL CODE: 06122
TELEPHONE: 075-585-3467-3471-3492-3464
FAX: 075-585-3405
E-MAIL: farmaco@unipg.it;
riccardi@unipg.it
PUBLICATIONS:
-
MIGLIORATI, G., NICOLETTI, I., PAGLIACCI, M.C., D'ADAMIO, L., RICCARDI C.
Interleukin-4 protects double-negative and CD4 single-positive thymocytes
from dexamethasone-induced apoptosis. Blood, 81:1352-1358, 1993.
-
MIGLIORATI, G., NICOLETTI, I., D'ADAMIO, F., SPRECA, A., PAGLIACCI, C., RICCARDI,
C. Dexamethasone induces apoptosis in mouse natural killer cells and cytotoxic
T lymphocytes. Immunology, 81: 21-26, 1994.
-
DELFINO, D.V., PATRENE, K.D., DE LEO, A.B., DE LEO, R., HERBERMANN, R.B.,
BOGGS, S.S. Role of CD44 in the development of NK cells from precursors in
long-term cultures of mouse bone marrow. J. Immunol. 154: 5171-5179,
1994.
-
NOCENTINI, G., RONCHETTI, S., BARTOLI, A., TESTA, G., D'ADAMIO, F., RICCARDI,
C., MIGLIORATI, G. T cell receptor an alternatively spliced product of the
T cell receptor gene. Eur. J. Immunol. 25: 1405-1409, 1995.
-
AYROLDI, E., CANNARILE, L., MIGLIORATI, G., BARTOLI, A., NICOLETTI, I., RICCARDI,
C. CD44(Pgp-1) inhibits CD3 and dexamethasone-induced apoptosis.
Blood, 86: 2672-2678, 1995.
-
SPINOZZI, F., NICOLETTI, I., AGEA, E., BELIA, S., MORACA, R., MIGLIORATI,
G., RICCARDI, C., GRIGNANI, F., BERTOTTO, A. IL-4 is able to reverse the
CD2-mediated negative apoptotic signal to CD4- CD8- and/or T lymphpocytes.
Immunology, 86: 379-384, 1995.
-
FIORUCCI, S., SANTUCCI, L., MIGLIORATI, G., RICCARDI C., AMOROSI, A., MANCINI,
A., ROBERTI, R., MORELLI, A. Isolated guinea pig gastric chief cells express
tumor necrosis factor receptors coupled with the sphingomyelin pathway.
Gut, 38: 182-189, 1996.
-
SPINOZZI, F., AGEA, E., BISTONI, O., FORENZA, N., MONACO, A., BASSOTTI, G.,
NICOLETTI, I., RICCARDI, C. Increased allergen-specific, steroid-sensitive
T cells in bronchoalveolar lavage fluid from patients with asthma. Ann.
Intern. Med. 124: 223-227, 1996.
-
DELFINO, D.V., PATRENE, K.D., LU, J., DE LEO, A., DE LEO, R., HERBERMAN ,R.B.,
BOGGS, S.S. Natural killer cell precursors in the CD44neg/dim T-cell receptorneg
population of mouse bone marrow. Blood, 87, 2394-2400, 1996.
-
SANTUCCI, L., FIORUCCI, S., CHIOREAN, M., BRUNORI, P.M., DI MATTEO, F.M.,
SIDONI, A., MIGLIORATI, G., MORELLI, A. Interleukin 10 reduces lethality
and hepatic injury induced by lipopolysaccharide in galactosamine-sensitized
mice. Gastroenterology, 111: 736-744, 1996.
RESEARCH GROUP MEMBERS:
-
Saso Luciano, R.U.
-
Casini Maria Luisa, D.DR.
AFFILIATION :
Istituto di Farmacologia e Farmacognosia
Facoltà di Farmacia
Università di Roma 'La Sapienzà
ADDRESS: P.le Aldo Moro, 5
CITY: Roma
POSTAL CODE: 00185
TELEPHONE: 06-49912481
FAX: 06-49912480
E-MAIL: saso@axrma.uniroma1.it
PUBLICATIONS:
-
GUGLIELMOTTI, A., SILVESTRINI, B., SASO, L., ZWAIN, I.H. AND CHENG ,C.Y.
Chronic inflammatory response in the rat can be blocked by bindarit.
Biochem. Mol. Biol. Int. 29: 747-756, 1993.
-
SASO, L., SILVESTRINI, B. AND CHENG, C.Y. The use of high performance
electrophoresis chromatography for the micropurification of cerebrospinal
fluid proteins in the rat. Anal. Biochem. 212: 315-324, 1993.
-
SASO, L., SILVESTRINI, B., GUGLIELMOTTI, A., LAHITA, R. AND CHENG, C.Y. Abnormal
glycosylation of a2-macroglobulin, a non-acute-phase protein,
in patients with autoimmune diseases. Inflammation 17: 465-479, 1993.
-
SASO L., SILVESTRINI B., LAHITA R., AND CHENG C.Y. Changes of immunoreactivity
in a1-antitrypsin in patients with autoimmune diseases.
Inflammation 17: 383-400, 1993.
-
LI, A.H.Y., ZWAIN, I.H., PINEAU, C., CAZZOLLA, N., SASO, L., SILVESTRINI,
B., BARDIN, C.W. AND CHENG, C.Y. Response of 2-macroglobulin messenger
ribonucleic acid expression to acute inflammation in the testis is different
from the response in the liver and brain. Biol. Reprod. 50: 1287-1296,
1994
-
GIACOMELLI, S., LEONE, M.G., GRIMA, J., SILVESTRINI, B. AND CHENG, C.Y.
Astrocytes synthesize and secrete prostaglandin D synthetase in vitro.
Biochim. Biophys. Acta 1310: 269-276, 1996
-
SASO, L., CASINI, M.L., MATTEI, E., VALENTINI, G. AND MAZZANTI, G. . -Hydroxy
acids, anti-aging compounds, protect albumin against heat-induced denaturation.
Phytother. Res. 10 : In press, 1996.
RESEARCH GROUP MEMBERS :
-
Sorrentino Ludovico, P.O.
-
Calignano Antonio, R.U:
-
Cirino Giuseppe, R.U.
-
Cicala Carla, B.PDR.
-
Sorrentino Raffaella, B.PDR.
-
Mancuso Franca, B.PDR
AFFILIATION :
Dipartimento di Farmacologia Sperimentale
Facoltà di Farmacia
Università di Napoli Federico II
ADDRESS: Via Domenico Montesano 49
CITY: Napoli
POSTAL CODE: 80131
TELEPHONE: 081-7486402
FAX: 081-7486403
PUBLICATIONS :
-
CIRINO G., CICALA C., SORRENTINO L. AND J.L. BROWNING. Human recombinant
non pancreatic secreted platelet phospholipase A2 has anticoagulant activity
in vitro on human plasma. Thromb. Res. 70 : 337-342, 1993.
-
CALIGNANO A., PERSICO P., MANCUSO F., SORRENTINO L. Endogenous nitric oxide
modulates morphine-induced changes in locomotion and food intake in mice.
Eur. J. Pharmacol. 231 : 415-419, 1993.
-
CIRINO G., CICALA C., SORRENTINO L., SORRENTINO R., BROWNING J.L. AND PAGE
C.P. Human recombinant secreted phospholipase A2 has antiaggregatory effect
in vivo and in vitro in rat and guinea pig. Eur. J.Pharmacol.
252 : 147-154, 1994.
-
CIRINO G., CICALA C., SORRENTINO L., FRANCESCO M. MAIELLO AND J.L. BROWNING.
Human recombinant secreted phospholipase A2 induces a synovitis-like inflammation
in rat air pouch. J. Rheumatol. 21 : 824-829, 1994.
-
WALLACE J.L., REUTER B., CICALA C., MCKNIGHT W., GRISHAM M., CIRINO G. Novel
NSAID derivatives with markedly reduced ulcerogenic properties in the rat.
Gastroenterology 107 : 173-179, 1994.
-
MANCUSO F., CALIGNANO A., SORRENTINO L. Endogenous nitric oxide modulates
behavioural effects elicited by substance P in rat. Eur. J. Pharmacol.
271 : 329-333, 1994.
-
WALLACE, J.L., MCKNIGHT W., DEL SOLDATO, P., BAYDOUN A.R. AND G. CIRINO.
Anti-thrombotic effect of a nitric-oxide releasing, gastric-sparing aspirin
derivative. J. Clin. Invest. 96 : 2711-2718, 1995.
-
MANCUSO F., FLOWER R.J., PERRETTI M. Leukocyte transmigration, but not rolling
or adhesion, is selectively inhibited by dexamethasone in the hamster
post-capillary venule. J. Immunol. 155 : 377-386, 1995.
-
CIRINO,G., CICALA C., BUCCI, M.R., MARAGANORE J.M.. AND STONE S.R. Thrombin
functions as an inflammatory mediator through activation of its receptor.
J. Exp. Med. 183 : 821-827, 1996.
RESEARCH GROUP MEMBERS :
-
Zilletti Lucilla, P.O.
-
Ciuffi Mario P.A.
-
Franchi-Micheli S. T.L.
-
Mugnai Sabrina. D.DR.
-
D'Alfonso Caterina B.
AFFILIATION :
Dipartimento di Farmacologia Preclinica e Clinica "Mario Aiazzi Mancini"
Facoltà di Medicina e Chirurgia
Università degli Studi di Firenze
ADDRESS: Viale G.B. Morgagni 65
CITY: Firenze
POSTAL CODE: 50134
TELEPHONE: 055-4237-411,407,423
FAX: 055-4361613
PUBLICATIONS:
-
CIUFFI M., GENTILINI G., FRANCHI-MICHELI S., ZILLETTI L. Effect of
21-amanosteroid U74500A (pregna-1,4,9(11)
triene-3,20-dione,21-(4-(5,6-bisdietylamino)-2-pyridinyl)-16-methyl,HCl(16
alpha)), on rat brain cortex lipid peroxidation induced "in vivo" by
iron-carbohydrate. Biochem. Pharmacol. 47:2181-2186,1994.
-
CIUFFI M., TARLINI L., MUGNAI S., FRANCHI-MICHELI S., ZILLETTI L. Hemoglobin
affects lipid peroxidation and prostaglandin E2 formation in rat corticocerebral
tissues in vitro. Biochem. Pharmacol. 52:97-103,
-
FAILLI P., CECCHI E., RUOCCO C., FAZZINI A., GIOTTI A. Effects of L-and
D-arginine and some related esters on the cytosolic mechanisms of
a-thrombin-induced human platelet activation. Brit. J. Pharmacol.
110:213,218, 1993.
-
FAILLI P., RUOCCO C., DE FRANCO R., CALIGIURI A., GENTILINI A., GIOTTI A.,
GENTILINI P., PINZANI M. The mito-genic effect of platelet-derived growth
factor in human hepatic stellate cells requires calcium influx. Amer.
J. Physiol. Cell Physiol. 269:C1133-C1139, 1995.
-
FAILLI P., TESCO G., RUOCCO C., GINESTRONI A., AMADUCCI L., GIOTTI A., SORBI
S. The effect of tetraethylammonium on intracellular calcium concentration
in Alzheimer's disease fibroblasts with APP, A182 and E5-1 missense
mutations. Neurosci. Lett. 208:216-218, 1996.
-
GENTILINI G., FRANCHI-MICHELI S., MUGNAI S., BINDI D., ZILLETTI L. GABA-mediated
inhibition of the anaphylactic response in the guinea-pig trachea. Brit.
J. Pharmacol.. 115:389-394, 1995.
-
ZILLETTI L., CIUFFI M., FRANCHI-MICHELI S., FUSI F., GENTILINI G., MONETI
G., VALOTI M., SGARAGLI G. P. Cyclooxygenase activity of hemoglobin.
Methods-Enzymology. 30: 562-573,1994.
Torna al sommario