SIF - Societą
Italiana di Farmacologia
"SIF - La Ricerca Farmacologica in Italia"
CHEMOTHERAPY
RESEARCH GROUP MEMBERS :
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Bertazzoni Minelli Elisa, P.O.
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Benini Anna, B.
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Mazzon Ilaria, B.
AFFILIATION :
Istituto di Farmacologia,
Facoltą di Medicina e Chirurgia
Universitą di Verona
ADDRESS: c/o Policlinico Borgo Roma
CITY: Verona
POSTAL CODE: 37134
TELEPHONE: 045-8098603, 8074244
FAX: 045-581111
PUBLICATIONS:
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BERTAZZONI MINELLI E., BENINI A., BEGHINI A.M., CERUTTI R., NARDO G., Bacterial
faecal flora in healthy women of different ages. Microb. Ecol. Health
Dis. 6: 43-51, 1993.
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BERTAZZONI MINELLI E., BENINI A. Effects of six antimicrobial drugs on rat
intestinal flora: is the rat model of predictive value in clinical practice?
Microb. Ecol. Health Dis. 6 : 53-66, 1993.
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BASSI C., PEDERZOLI P., VESENTINI S., CAVALLINI G., BOVO P., LOMBARDI D.,
ABBAS H., BENINI A., BERTAZZONI M.E. Behavior of antibiotics during human
necrotizing pancreatitis. Antimicrob. Agents Chemother. 38: 830-836,
1994.
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CRUCIANI M., BERTAZZONI MINELLI E., MIRANDOLA M., LUZZATI R., MERIGHI M.,
LAZZARINI L., GATTI G., VENTO S., MAZZI R., LAZZARINI L., MALENA M., BENINI
A., CAZZADORI A., PIEMONTE G., BASSETTI D., CONCIA E. Twice-weekly dapsone
for primary prophylaxis of Pneumocystis carinii pneumonia in
HIV-1 infection: comparative efficacy and pharmacokinetic data. Clin.
Microbiol. Infection 2: 30-35, 1996.
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BERTAZZONI MINELLI E., BENINI A., BASSI C., ABBAS H., FALCONI M., PEDERZOLI
P. Antimicrobial activity of human pancreatic juice and its interaction with
antibiotics. Antimicrob. Agents Chemother. 40: 2099-2105, 1996.
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BERTAZZONI MINELLI E., BENINI A., MUNER A., BASSI C., ABBAS H., PEDERZOLI
P. Pefloxacin penetration into human necrotic pancreatic tissue. J.
Antimicrob. Chemother. 38: 237-243, 1996
RESEARCH GROUP MEMBERS:
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Braga Pier Carlo, P.A.
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Dal Sasso Monica, D.DR.
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Sala Maria Teresa, B.
AFFILIATION:
Centro di Studio e Ricerca in Farmacologia Respiratoria
Facoltą di Medicina e Chirurgia
Universitą degli Studi di Milano
ADDRESS: Via Vanvitelli, 32
CITY: Milano
POSTAL CODE: 20129
TELEPHONE: 02 - 70146-363, 233
FAX: 02 - 70146-363
PUBLICATIONS:
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BRAGA P.C., DAL SASSO M., MACI S, BONDIOLOTTI G., FONTI E., REGGIO S. Penetration
of brodimoprim into human neutrophils and intracellular activity. Antimicr.
Agents Chemother. 40: 2392-2398, 1996.
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BRENCIAGLIA M.I., FORNARA A.M., SCALTRITO M.M., BRAGA P.C., DUBINI F. Activity
of amoxicillin, metronidazole, bismuth salicilate and six aminoglicosides
against Helicobacter pylori. J. Chemother. 8 : 52-54, 1996.
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BRAGA P.C., MACI S., DAL SASSO M., BOHN M. Experimental evidences for the
role of subinhibitory concentrations or rilopirox, nystatin and fluconazole
on adherence of Candida spp. to vaginal epithelial cells. Chemoterapy,
42: 259-265, 1996.
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BRAGA P.C., REGGIO S. Correlation between reduction of surface hydrophobicity
of S. aureus and the decrease in its adhesiveness induced by sub-inhibitory
concentrations of brodimoprim. Pharmacol Res. 32 : 315-319, 1995.
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BRAGA P.C., MACI S., DAL SASSO M., PIATTI G., BOHN M. Alterations of surface
morphology of Candida albicans produced by rilopirox: a scanning electron
microscopy study. J. Chemother. 7 : 519-524, 1995.
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BRAGA P.C., DAL SASSO M., MACI S., ALLEGRA L., FONTI E., GHESSI A., REGGIO
S. Influence of brodimoprim on polymorphonuclear leukocyte phagocytosis and
oxidant radical production. Chemotherapy .41: 360-367, 1995.
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BRAGA P.C., PIATTI G., LIMOLI A., DAL SASSO M., MACI S. Neltenexine morphological
investigation of protection against elastase-induced emphysema in rats.
Drugs Expt. Clin. Res. 21: 51-57, 1995.
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BRAGA P.C., DAL SASSO M., MACI S., PIATTI G., DANNHORN D.R., BOHM M. Inhibition
of Candida albicans adhesiveness to human buccal and vaginal cells by sub-MIC
of rilopirox. Arzneim. Forsch Drug Res. 45: 84-87, 1995.
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BRAGA P.C., DAL SASSO M., MACI S., REGGIO S., PIATTI G. Influence of
sub-inhibitory concentrations of brodimoprim and trimethoprim on the
adhesiveness, hydrophobicity, hemagglutination and motility of Escherichia
coli. Chemotherapy 41: 50-58, 1995.
RESEARCH GROUP MEMBERS:
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De Sarro Angela, P.A.
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Naccari Francesco, P.A.
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Ammendola Domenico, T.L.
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Nava Felice, B.
AFFILIATION:
Istituto di Farmacologia
Facoltą di Medicina e Chirurgia
Universitą di Messina
ADDRESS: Piazza XX Settembre, 4
CITY: Messina
POSTAL CODE: 98122
TELEPHONE: 090-712533
FAX: 090-661029
PUBLICATIONS:
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DE SARRO G.B. AND A. DE SARRO - Anticonvulsant properties of non-competitive
antagonists of the N-methyl-D-Aspartate receptor in genetically epilepsy-prone
rats: comparison with CPPene. Neuropharmacology, 32 :
51-58, 1993.
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DE SARRO G.B., DONATO DI PAOLA E., DE SARRO A., VIDAL M.J. - L-arginine
potentiates excitatory amino acid-induced seizures elicited in the deep
prepiriform cortex. Eur. J. Pharmacol., 230 : 151-158,
1993.
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DE SARRO A., ZAPPALą M., CHIMIRRI A., GRASSO S., DE SARRO G.B. -
Quinolones potentiate cephazolin-induced seizures in DBA\2 mice. Ant.
Agents Chemother., 37 : 1497-1503, 1993.
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DE SARRO G., ONGINI E., BERTORELLI R., AGUGLIA U., DE SARRO A. - Excitatory
amino acid neurotransmission through both NMDA and non-NMDA receptors is
involved in the anticonvulsant activity of felbamate in DBA\2 mice. Eur.
J. Pharmacol., 262 : 11-19, 1994.
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DE SARRO G., AMMENDOLA D., NAVA F., DE SARRO A. - Effects of some excitatory
amino acid antagonists on imipenem-induced seizures in DBA\2 mice. Brain
Res., 671 : 131-140, 1995.
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DE SARRO A., AMMENDOLA D., ZAPPALą M., GRASSO S., DE SARRO G.B. -
Relationship between structure and convulsant properties of some -lactam
antibiotics following intracerebroventricular microinjection in rats. Ant.
Agents Chemother., 39 : 232-237, 1995.
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SAIJA A., PRINCI P., LANZA M., SCALESE M., ARAMNEJAD E., DE SARRO A. - Systemic
cytokine administration can affect blood-brain barrier permeability in the
rat. Life Sci., 56 : 775-784, 1995.
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DE SARRO G., CHIMIRRI A., DE SARRO A., GITTO R., GRASSO S., GIUSTI P., CHAPMAN
A. - GYKI 52466 and related 2,3-benzodiazepines as anticonvulsant agents
in DBA/2 mice. Eur. J. Pharmacol., 294 : 411-422, 1995.
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DE SARRO G., NAVA F., AGUGLIA U., DE SARRO A. - Lamotrigine potentiates the
antiseizure activity of some anticonvulsants in DBA/2 mice.
Neuropharmacology, 35 : 153-158, 1996.
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DE SARRO G., DE SARRO A., AMMENDOLA D., PATEL S. - Lack of development of
tolerance to anticonvulsant activity of CGP 37849 and CGP 39551 in genetically
epilepsy-prone rats. Brain Res., 262 : 11-19, 1996.
RESEARCH GROUP MEMBERS :
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Fraschini Franco, P.O
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Ferrara Franca, A.O
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Scaglione Francesco, T.L
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Demartini Germana, T.L
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Dugnani Silvana, T.L
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Lucini Valeria, T.L
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Maccarinelli Giuseppina, T.L
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Nonno Romolo, D.DR
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Arcidiacono Mauro, D.DR
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Angeloni Deborah, D.DR
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Stankof Bojidar, Professore a Contratto
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Pannacci Marilou, B.
AFFILIATION :
Dipartimento di Farmacologia, Chemioterapia e Tossicologia Medica
Facoltą di Medicina e Chirurgia
Universitą degli Studi di Milano
ADDRESS: Via Vanvitelli, 32
CITY: Milano
POSTAL CODE: 20129
TELEPHONE: 02-718937, 70146.305
FAX: 02-718687
E-MAIL: Chemio@Imiucca.csi.unimi.it
PUBLICATIONS:
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STANKOV, S. CAPSONI, V. LUCINI, J. FAUTECK, S. GATTI, B. GRIDELLI, G. BIELLA,
B. COZZI AND F. FRASCHINI. Autoradiographic localization of putative melatonin
receptors in the brains of two old world primates: Cercopithecus aethiops
and Papio ursinus. Neuroscience 52:459-468, 1993
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SCAGLIONE, J.P. PINTUCCI, G.F. TASSI, G. MACCARINELLI, S. DUGNANI, G. DEMARTINI
AND F. FRASCHINI. Penetration of clarithromycin into oral and respiratory
tissues. Drug. Invest. 6:104-109, 1993
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STANKOV, M. GERVASONI, F. SCAGLIONE, R. PEREGO, D. COVA, L. MARABINI AND
F. FRASCHINI. Primary pharmaco-toxicological evaluation of 2-iodio-melatonin,
a potent melatonin agonist. Life Sci. 53:1357-1365, 1993
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SCAGLIONE, S. DUGNANI, G. DEMARTINI, M. SAUDELLI, G. GALMOZZI, F. FRASCHINI.
The postantibiotic effect of clarithromycin and its major human metabolite,
14-hydroxy clarithromycin. J. Antimicrob. Chemother. 32:507-509, 1993
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STANKOV, MØLLER, V. LUCINI, S. CAPSONI, F. FRASCHINI. A carnivore
species (Canis familiaris) expresses circadian melatonin rhythm in the peripheral
blood and melatonin receptors in the brain. Eur J Endocrinol 131:191-200,
1994.
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ESPOSTI, M. MARIANI, G. DEMARTINI, V. LUCINI, F. FRASCINI, W. WITTKOWSKI,
B. STANKOV. The adult human cerebellum is a target of the neuroendocrine
system involved in the circadian timing. Neurosci Lett 179:60-64,
1994.
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SCAGLIONE, F. TRISCARI, G. DEMARTINI, M. ARCIDIACONO, C. COCUZZA, F. FRASCHINI.
Concentrations of ceftibuten in bronchial secretions. Chemotherapy,
41:229-233, 1995.
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SCAGLIONE, S. DUGNANI, G. DEMARTINI, M. ARCIDIACONO, C. COCUZZA, F. FRASCHINI.
Bactericidal kinetics of an in vitro infection model of once daily ceftriaxone
plus amikacin against gram-positive and gram - bacteria. Chemotherapy,
41:239-246, 1995.
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FERINI-STRAMBI, A. OLDANI, M. ZUCCONI, B. STANKOV, C. CASTRONOVO, F. FRASCHINI,
S. SMIRNE. Triazolam and melatonin effects on cardiac autonomic function
during sleep. Clin. Neuropharmacol. 18:405-409,
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MAZZUCHELLI, S. CAPSONI, D. ANGELONI, F. FRASCHINI, B. STANKOV. The Melatonin
receptor in the humain brain: cloning experiments and distribution studies.
Mol. Brain Res., 39: 117-126, 1996.
RESEARCH GROUP MEMBERS:
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Giraldi Tullio, P.O.
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Perissin Laura, R.U.
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Zorzet Sonia, R.U. *
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Rapozzi Valentina, T.L.
AFFILIATION:
Sezione di Farmacologia, Dipartimento di Scienze e Tecnologie Biomediche
Facoltą di Medicina e Chirurgia
Universitą di Udine
* Sezione di Farmacologia, Dipartimento di Scienze Biomediche
Facoltą di Farmacia
Universitą di Trieste
ADDRESS: Piazzale Kolbe 4
CITY: Udine
POSTAL CODE: 33100
TELEPHONE: 0432-547117
FAX: 0432-547210
E-MAIL: giraldi@cc.uniud.it
PUBLICATIONS :
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CARTEI, G., CARTEI, F., CANTONE, A., CAUSARANO, D., GENCO, G., TOBALDIN,
A.., INTERLANDI, G., AND GIRALDI, T. Cisplatin-cyclophosphamide-mitomycin
combination chemothereapy with supportive care versus supportive care alone
for treatment of metastasis non-small-cell lung cancer. JNCI 85: 794-800,
1993.
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PERISSIN, L., ZORZET, S., RAPOZZI, V., AND GIRALDI, T. A non-invasive simple
method for measurement of urinary excretion of melatonin in undisturbed mice.
J. Pineal Res. 15: 138-140, 1993.
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GIRALDI, T., PERISSIN, L:, ZORZET, S:, RAPOZZI, V:, AND RODANI, M.G. Metastasis
and neuroendocrine system in stressed mice.. Intern. J. Neurosci.
74: 265-278, 1994.
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PERISSIN, L., ZORZET, S:; RAPOZZI, V., PAOLETTI, D:, AND GIRALDI, T. Seasonal
dependency of the effects of experimental stressors on tumor metastasis in
mice bearing Lewis lung carcinoma.. Chronobiologia 1/2 99-103, 1994.
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ZORZET, S., PERISSIN, L., RAPOZZI, V., PACOR, S., AND GIRALDI, T. Effects
of prolonged treatment with dacarbazine on tumour metastatic potential in
mice bearing Lewis lung carcinoma. Clin. Exp. Metastasis 13: 97-104,
1995.
RESEARCH GROUP MEMBERS :
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Mazzei Teresita, P.O.
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Mini Enrico, P.A.
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Novelli Andrea, R.U.
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Coronnello Marcella, T.L.
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Pesciullesi Alessandra, DDR
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Morganti Maria, D.DR.
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Carotti Stefania, B.
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Biondi Cristina, B.
-
Fallani Stefania, B.
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Cassetta Maria Iris, B.
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Conti Silvia, B.
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Caciagli Barbara, B.
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Napoli Cristina, B.
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Nobili Stefania, S.S.
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Rossi Susanna, S.S.
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Dentico Patrizia, S.S.
AFFILIATION:
Dipartimento di Farmacologia Preclinica e Clinica "Mario Aiazzi Mancini"
Unitą di Chemioterapia
ADDRESS: Viale Morgagni 65,
CITY: Firenze
POSTAL CODE: 50134
TELEPHONE: 055-431720 (adm. of.), 4237-405, 411(operator), 4222603,
4237-410, 438, 439 (lab)
FAX: 055-416680; 4361613
E-MAIL : MAZZEI@Stat.Ds.UNIFI.IT
PUBLICATIONS :
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CAPACCIOLI, S., DI PASQUALE, G., MINI, E., MAZZEI, T.,AND CAPACCIOLI, S.
Cationic lipids improve antisense oligonucleotide uptake and prevent degradation
in cultured cells and in human serum. Biochem. Biophys. Res. Comm.
197: 818-825, 1993.
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DE LALLA, F., NOVELLI, A., PELLIZZER, G., MILOCCHI, F., VIOLA, R.,
RIGON, A., STECCA, C., DAL PIZZOL, V., FALLANI, S., AND PERITI, P. Regional
and systemic prophylaxis with teicoplanin in monolateral and bilateral total
knee replacement procedures: study of pharmacokinetics and tissue penetration.
Antimicrobial Agents Chemother. 37: 2693-2698, 1993.
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MAZZEI, T., SURRENTI, C., NOVELLI, A., CRISPO, A., FALLANI, S., CARLą,
V., SURRENTI, E. AND PERITI, P. Pharmacokinetics of azithromycin in patients
with impaired hepatic function. J. Antimicrobial Chemother.
31: 57-63, 1993.
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QUATTRONE, A., PAPUCCI, L., MORGANTI, M., CORONNELLO, M., MINI, E., MAZZEI,
T., COLONNA, F.P., GARBESI, A., AND CAPACCIOLI, S. Inhibition of MDR1 gene
expression by antimessenger oligonucleotides lowers multiple drug
resistance.Oncol. Res. 6: 311-320,1994.
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QUATTRONE, A., PAPUCCI, L., SCHIAVONE, N., MINI, E., AND CAPACCIOLI, S.
Intracellular enhancement of intact antisense oligonucleotide steady-state
levels by cationic lipids. Anticancer Drug Design. 9: 549-553, 1994.
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MAZZEI, T., TONELLI, F., NOVELLI, A., FICARI, F., MAZZONI, C., ANASTASI,
A., AND PERITI, P. Comparative penetration of cefotetan into suction blister
fluid and tissue homogenates in patients undergoing abdominal surgery. Cefotetan
tissue penetration. Antimicrobial Agents Chemother. 38: 2221-2223,
1994.
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ARCANGELI, A., BIANCHI, L., BECCHETTI, A., FARAVELLI, L., CORONNELLO, M.,
MINI, E., OLIVOTTO, M., AND WANKE, E. A novel inward-rectifying K+
current with a cell-cycle dependence governs the resting potential of mammalian
neuroblastoma cells. J. Physiol. 455-471, 1995.
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CREE, I.A., PAZZAGLI, M., MINI, E., MAZZEI, T., HUNTER, E.M.M., SUTHERLAND,
L.A., PINZANI, P., GERLI, A., AND ANDREOTTI, P.E. Methotrexate chemosensitivity
by ATP bioluminescence in human leukemia cell lines and in breast cancer
primary cultures: comparison of the TCA-100 assay with a clonogenic assay.
Anticancer Drugs. 6: 398-404, 1995.
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MAZZEI, T., TONELLI, F., MINI, E., MAZZONI, P., PESCIULLESI, A., VALANZANO,
R., FICARI, F., BIONDI, C.,AND PERITI, P. Flow cytometric analysis of DNA
ploidy and cell proliferation in colorectal carcinoma. Anticancer Res.
15: 2247-2254, 1995.
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NOVELLI, A., MAZZEI, T., MELI, E., CONTI, S., FALLANI, S., PERITI, P. Clinical
pharmacokinetics of meropenem after single or multiple im administration
in patients. J. Antimicrobial Chemother. 37: 775-781, 1996.
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