SIF - Societą
Italiana di Farmacologia
"SIF - La Ricerca Farmacologica in Italia"
PHARMACOLOGY OF THE
CENTRAL NERVOUS SYSTEM II
RESEARCH GROUP MEMBERS:
-
Corradetti Renato, P.A.
-
Pugliese Anna Maria, B.PDR.
-
Passani Maria Beatrice, B.PDR.
AFFILIATION:
Dipartimento di Farmacologia Preclinica e Clinica
"Mario Aiazzi-Mancini"
Facoltą di Medicina e Chirurgia
Universitą di Firenze
ADDRESS: Viale G.B. Morgagni, 65
CITY: Firenze
POSTAL CODE: 50134
TELEPHONE: 055-4237-411, 429, 455
FAX: 055-4361-613
E-MAIL: neuroef@stat.ds.unifi.it
PUBLICATIONS:
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PASSANI, M.B., PUGLIESE, A.M., AZZURRINI, M. AND CORRADETTI, R. Effects of
DAU 6215, a novel 5-hydroxytryptamine3 (5-HT3) antagonist on electrophysiological
properties of the rat hippocampus. Brit. J. Pharmacol. 112: 695-703,
1994.
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BALLERINI, L., CORRADETTI, R., NISTRI, A., PUGLIESE, A.M. AND STOCCA, G.
Electrophysiological interactions between 5-hydroxytryptamine and thyrotropin
releasing hormone on rat hippocampal CA1 neurons. Eur. J. Neurosci.
6: 953-960, 1994.
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PUGLIESE, A.M., BALLERINI, L., PASSANI, M.B. AND CORRADETTI, R. EPSP-Spike
potentiation during primed burst-induced long-term potentiation in the CA1
region of rat hippocampal slices. Neuroscience 62: 1021-1032, 1994.
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FLETCHER, A., FORSTER, E.A., BILL, D.J., BROWN, G., CLIFFE, I.A., HARTLEY,
J.E., JONES, D.E., MCLENACHAN, A., STANHOPE, K.J., CRITCHLEY, D.J.P., CHILDS,
K.J., MIDDLEFELL, V.C., LANFUMEY, L., CORRADETTI, R., LAPORTE, A.M., GOZLAN,
H., HAMON, M., DOURISH, C. Electrophysiological, biochemical, neurohormonal
and behavioural studies with WAY-100635, a potent, selective, and silent
5-HT1A receptor antagonist. Behav. Brain Res. 73: 337-353, 1995.
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PASSANI, B.M. AND CORRADETTI, R. Therapeutic potentials of DAU 6215 (Itasetron),
a novel 5-HT3 receptor antagonist, in the treatment of central nervous disorders.
CNS Drug Reviews 2: 195-213, 1996.
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CORRADETTI, R., LE POUL, E., LAARIS, N., HAMON, M. AND LANFUMEY, L.
Electrophysiological effects of WAY 100635
(N-(2-(-4(2metoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cycloexane
carboxamide) on dorsal raphe serotoninergic neurones and CA hippocampal pyramidal
cells in vitro. J. Pharmacol. Exp. Ther. 278: 679-688. 1996.
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PUGLIESE, A.M. AND CORRADETTI, R. Effects of the antiepileptic drug felbamate
on long-term potentiation in the CA1 region of rat hippocampal slices.
Neurosci. Lett. 215: 21-24, 1996.
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PUGLIESE, A.M., PASSANI, M.B., PEPEU, G. AND CORRADETTI, R. Felbamate decreases
synaptic potentials and CA1 pyramidal cells in rat hippocampal slices. J.
Pharmacol. Exp. Ther. 279: In press, 1996.
RESEARCH GROUP MEMBERS:
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Corsini Giovanni Umberto, P.O.
-
Vaglini Francesca,T.L.
-
Maggio Roberto, R.U.
-
Fornai Francesco, C.L.
AFFILIATION:
Istituto di Farmacologia
Facoltą di Medicina e Chirurgia
Universitą degli Studi di Pisa
ADDRESS: Via Roma, 55
CITY: Pisa
POSTAL CODE: 56100
TELEPHONE: 050-560109,560509
FAX: 050-551434
E-MAIL: gcorsini@drugs.med.unipi.it
r.maggio@drugs.med.unipi.it
PUBLICATIONS:
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VAGLINI F., FASCETTI F., FORNAI F., MAGGIO R. AND CORSINI G.U. (+)MK-801
prevents the DDC-induced enhancement of MPTP toxicity in mice. Brain
Res. 668:194-203, 1994.
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FORNAI F., DYBDAL D.J., PROCTOR M.R., GALE K. Focal intracerebral elevation
of L-lactate is anticonvulsivant. Eur. J. Pharmacol. 254 : R1-R2,
1994.
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BARBIER P., RENZETTI A.R., TURBANTI L., DI BUGNO C., FORNAI F., VAGLINI F.,
MAGGIO R. AND CORSINI G.U. Stereoselective inhibition of muscarinic receptor
subtypes by the stereoisomers related to rociverine. Eur. J.
Pharmacol.290:125-132, 1995.
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FORNAI F., ALESSANDRI' M.G., FASCETTI F., VAGLINI F. AND CORSINI G.U.
Clonidine Suppresses 1-Methyl-4-Phenyl-1,2,3,6-Tethrahydropyridine-Induced
Reductions of Striatal Dopamine and Tyrosine Hydroxylase Activity in Mice.
J. Neurochem. 65: 704-709, 1995.
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FORNAI F., BASSI L., TORRACCA M.T., SCALORI V. AND CORSINI G.U. Norepinephrine
loss exacerbates methamphetamine-induced striatal dopamine depletion in mice.
Eur. J. Pharmacol. 283: 99-102 1995.
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MAGGIOR., BARBIER P., TOSO A., BARLETTA D. AND CORSINI G.U. Sodium nitroprusside
induces internalizazion of muscarinic receptors stably expressed in cho cell
line. J. Neurochem. 65: 943-946, 1995.
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VAGLINI F., PARDINI C., MAGGIO R. AND CORSINI G.U. Role of excitatory amino-acids
in diethyldithiocarbamate-induced cell death in mesencephalic cultures.
Brain Res. 674: 127-132, 1995.
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VAGLINI F., FASCETTI F. ,TEDESCHI D., CAVALLETTI M., FORNAI F. AND CORSINI
G.U. Striatal MPTP levels do not necessarily correlate with striatal DA levels
after different combined treatments in mice. Neurodegeneration 5:129-136
1996.
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FORNAI F., VAGLINI F., MAGGIO R., BONUCCELLI U. AND CORSINI G.U. Excitatory
aminoacids and MPTP toxicity Adv. Neurol. 69:167-176, 1996.
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MAGGIO R., BARBIER P., FORNAI F. AND CORSINI G.U. Functional role of the
third cytoplasmatic loop in muscarinic receptor dimerization. J. Biol.
Chem. In press, 1996.
RESEARCH GROUP MEMBERS:
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Cuomo Vincenzo, P.O.
-
Cagiano Raffaele, P.A.
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Cortese Ida, P.A.
-
Renna Giuseppe, P.A.
-
Siro Brigiani Giovanni, P.A.
-
Carratł Maria Rosaria, R.U.
-
Giustino Arcangela, R.U.
-
Trabace Luigia, R.U.
-
De Salvia Maria A., T.L.
-
Di Giovanni Vincenzo, T.L.
AFFILIATION:
Istituto di Farmacologia
Facoltą di Medicina e Chirurgia
Universitą di Bari
ADDRESS: Policlinico, Piazza Giulio Cesare
CITY: Bari
POSTAL CODE: 70124
TELEPHONE: 080/5478448 - 5478439
FAX: 080/5478444
E-MAIL: cuomo@cimedoc.uniba.it
PUBLICATIONS:
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CARRATU' M.R., RENNA G., GIUSTINO A., DE SALVIA M.A. AND V. CUOMO, Changes
in peripheral nervous system activity produced in rats by prenatal exposure
to carbon monoxide, Arch. Toxicol., 67 : 297-301, 1993.
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DI GIOVANNI V., CAGIANO R., DE SALVIA M.A., GIUSTINO A., LACOMBA C., RENNA
G. AND V. CUOMO, Neurobehavioral changes produced in rats by prenatal exposure
to carbon monoxide, Brain Res., 616 : 126-131, 1993.
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DI GIOVANNI V., CAGIANO R., CARRATU' M.R., DE SALVIA M.A., GIUSTINO A. AND
V. CUOMO, Alteration in the ontogeny of rat pup ultrasonic vocalization produced
by prenatal exposure to nitrogen dioxide, Psychopharmacology, 116 :
423-427, 1994.
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ROBERTS A.C., DE SALVIA M.A., WILKINSON L.S., COLLINS P. MUIR J.L., EVERITT
B.J., ROBBINS T.W., 6- Hydroxydopamine lesions of the prefrontal cortex in
monkeys enhance performance on an analog of the Wisconsin Card Sort Test:
possible interactions with subcortical dopamine, J. Neurosci., 14 :
2531-2544, 1994.
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CARRATU' M.R., LABATE M., DE SANTIS S., GIUSTINO A., DE SALVIA M.A. AND V.
CUOMO, Lectin binding pattern of Schwann cells and macrophages in
2,5-hexanedione-induced axonal degeneration in rats, Arch. Toxicol.,
69 : 160-164, 1995.
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DE SALVIA M.A., CAGIANO R., CARRATU' M.R., DI GIOVANNI V., TRABACE L. AND
V. CUOMO, Irreversible impairment of active avoidance behavior in rats prenatally
exposed to mild concentration of carbon monoxide, Psychopharmacology,
122 : 66-71, 1995.
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STEARDO L., MONTELEONE P., D'ISTRIA M., MAJ M. AND V. CUOMO, (+)
N-allylnormetazocine (SKF-10047) enhances N-acetyltransferase activity and
melatonin synthesis: preliminary evidence for a functional role of sigma
receptors in the rat pineal gland, J. Pharmacol. Exp. Ther., 275 :
845-849, 1995.
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POZZI L., TRABACE L., INVERNIZZI R., SAMANIN R., Intranigral GR-113808, a
selective 5-HT4 receptor antagonist, attenuates morphine-stimulated dopamine
release in the rat striatum, Brain Res., 692 : 265-268, 1995.
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GIUSTINO A., BECKETT S., BALLARD T., CUOMO V. AND MARSDEN C.A., Perinatal
cocaine reduces responsiveness to cocaine and causes alteration exploratory
behavior and visual discrimination in young-adult rats, Brain Res.,
728 : 149-156, 1996.
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STEARDO L., MONTELEONE P., D'ISTRIA M., SERINO I., MAJ M. AND CUOMO V., Sigma
receptor modulation of noradrenergic-stimulated pineal melatonin biosynthesis
in rats, J. Neurochem., 67 : 287-293, 1996.
RESEARCH GROUP MEMBERS:
-
De Caro Giuseppe, P.O.
-
Massi Maurizio, P.O.
-
Polidori Carlo, R.U.
-
Pompei Pierluigi, R.U.
-
Ciccocioppo Roberto, D.DR.
AFFILIATION :
Dipartimento di Scienze Farmacologiche e Medicina Sperimentale
Facoltą di Farmacia
Universitą di Camerino
ADDRESS: Via Scalzino, 3
CITY: Camerino
POSTAL CODE: 62032
TELEPHONE: 0737-40700, 40701, 40761, 40763, 633242, 632538, 633015
FAX: 0737-630618
E-MAIL: decaro@cambio.unicam.it;
massi@cambio.unicam.it; polidori@cambio.unicam.it;
pompei@cambio.unicam.it
PUBLICATIONS:
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PANOCKA, I., POMPEI, P., AND MASSI, M. Suppression of alcohol preference
in rats following risperidone, a serotonin 5-HT2 and dopamine D2 receptor
antagonist. Brain Res. Bull. 31: 595-599, 1993.
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PANOCKA, I., CICCOCIOPPO, R., POLIDORI, C., AND MASSI, M. The nucleus accumbens
is a site of action for the inhibitory effect of ritanserin on ethanol intake
in rats. Pharmacol. Biochem. Behav. 46: 857-862, 1993.
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CICCOCIOPPO, R., PANOCKA, I., POMPEI, P., DE CARO, G., AND MASSI, M. Selective
agonists at NK3 tachykinin receptors inhibit alcohol intake in Sardinian
alcohol-preferring rats. Brain Res. Bull. 33: 71-78, 1994.
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CICCOCIOPPO, R., POLIDORI, C., POMPEI, P., DE CARO, G., AND MASSI, M. Inhibition
of isotonic sodium chloride intake in the rat by selective tachykinin agonists.
Pharmacol. Biochem. Behav. 47: 609-615, 1994.
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POLIDORI, C., CICCOCIOPPO, R., EPSTEIN, A.N., DE CARO, G., AND MASSI, M.
Effect of tachykinins of the need-free sodium intake of female rats: a continuous
intracerebroventricular infusion study. Physiol. Behav. 56: 877-882,
1994.
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CICCOCIOPPO, R., PANOCKA, I., STEFANINI, E., GESSA, G.L., AND MASSI, M. Low
responsiveness to agents evoking 5-HT2 receptor-mediated behaviours in Sardinian
alcohol-preferring rats. Pharmacol. Biochem. Behav. 51: 21-27, 1995.
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CICCOCIOPPO, R., PANOCKA, I., POMPEI, P., POLIDORI, C., DE CARO, G., AND
MASSI, M. Subcutaneous injections of the tachykinin senktide reduce alcohol
intake in alcohol-preferring rats. Peptides 16: 533-537, 1995.
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POMPEI, P., RIFTINA, F., AND MCEWEN, B.S. Effect of adrenal steroids on
preproneurokinin-A gene expression in discrete regions of the rat brain.
Mol. Brain Res. 33:209-216, 1995.
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PANOCKA, I., CICCOCIOPPO, R., MOSCA, M., POLIDORI, C., AND MASSI, M. Effects
of the dopamine D1 receptor antagonist SCH 39166 on the ingestive behaviour
of alcohol-preferring rats. Psychopharmacology 120: 227-235, 1995.
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POLIDORI, C., CICCOCIOPPO, R., POMPEI, P., CIRILLO, R., AND MASSI, M. Functional
evidence for the ability of angiotensin AT1 receptor antagonists to cross
the blood-brain barrier in rats. Eur. J. Pharmacol. 307: 259-267,
1996.
RESEARCH GROUP MEMBERS:
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De Carolis Scotti Arsenia, Dir.
R.
-
Sagratella Stefano, 1° R.
-
Popoli Patrizia, 1° R.
-
Frank Claudio, R.
-
Domenici M. Rosaria, B.
-
Pčzzola Antonella, T.
AFFILIATION:
Laboratorio di Farmacologia
Istituto Superiore di Sanitą
ADDRESS: Viale Regina Elena, 299
CITY: Roma
POSTAL CODE: 00161
TELEPHONE: 06 49902387, 49902482
FAX: 06 49387104
E- MAIL: sagrat@iss.it
PUBLICATIONS:
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DOMENICI, M.R., LONGO, R., FRANK, C., SCOTTI DE CAROLIS, A., SAGRATELLA,
S. Protective action of 21-aminosteroids and MK 801 on Hypoxia-induced
electrophysiological changes in rat hippocampal slices. Eur. J.
Pharmacol.. 233:291-293, 1993.
-
BRONZETTI, E., CAPORALI, M.G., FELICI, L., NIGLIO, T., SCOTTI DE CAROLIS,
A., AMENTA, F. Muscarinic cholinoceptor subtypes in the rat frontoparietal
cortex after ipsilateral lesions of the nucleus basalis magnocellularis.
Pharmacology. 46:301-307, 1993.
-
SAGRATELLA, S., SCOTTI DE CAROLIS, A., DIANA, G., DOMENICI, M.R., POPOLI,
P. Selective reduction of hippocampal dentate frequency-potentiation in
striatally-lesioned rats with impaired place learning. Brain Res.
660: 66-77, 1994.
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POPOLI, P., PEZZOLA, A., DOMENICI, M.R., SAGRATELLA, S., DIANA, G.,
CAPORALI, M.G., BRONZETTI, E., VEGA, S., SCOTTI DE CAROLIS, A. Behavioural
and electrophysiological correlates of the quinolinic acid model of Huntington's
disease in rats. Brain Res. Bull. 35: 329-335, 1994.
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FERRÉ, S., POPOLI P., GIMENEZ-LLORT, L., FINNMAN, U.B., MARTINEZ,
E., SCOTTI DE CAROLIS, A., FUXE, K. Postsynaptic antagonistic interaction
between adenosine A1 and dopamine D1 receptors.
Neuroreport. 6: 73-76, 1994.
-
POPOLI, P., REGGIO, R., PEZZOLA, A., SCOTTI DE CAROLIS, A. The stimulation
of cholecystokinin receptors in the rostral nucleus accummbens significantly
antagonized the EEG and behavioural effects induced by phencyclidine in rats.
Psychopharmacology. 120: 156-161, 1995.
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LONGO, R., ZENG, Y.C., SAGRATELLA, S. Opposite modulation of 4-aminopyridine
and hypoxic hyperexcitability by A1 and A2 adenosine
ligands in rat hippocampal slices. Neurosci. Lett. 200: 21-24, 1995.
-
FRANK, C., ENGERT, F., TOKUTOMI, N., LUX, H.D. Different effects of baclofen
and GTPS on voltage - activated (Ca++ currents in rat hippocampal
neurons in vitro. Eur. J. Pharmacol.. 295: 87-92, 1996.
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DOMENICI, M.R., SCOTTI DE CAROLIS, A., SAGRATELLA, S., Block by
N6-phenyl-isopropil-adenosine of the electrophysiological and morphological
correlates of the hippocampal ischemic injury in the gerbil. Brit. J.
Pharmacol. 118: 1551-1559, 1996.
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POPOLI, P., FERRÉ, S., PEZZOLA, A., REGGIO, R., SCOTTI DE CAROLIS,
A., FUXE, K. Stimulation of adenosine A1 receptors prevents the
EEG arousal due to dopamine D1 receptor activation in rabbits.
Eur. J. Pharmacol. 305: 123-126, 1996.
RESEARCH GROUP MEMBERS:
-
De Sarro Giovambattista, P.A.
-
Donato Di Paola Eugenio, R.U.
-
Rizzo Milena, R.U.
-
Gratteri Santo, T.L.
-
Gareri Pietro, B.
AFFILIATION:
Sezione di Farmacologia
Dipartimento di Medicina Sperimentale e Clinica
Facoltą di Medicina e Chirurgia di Catanzaro
Universitą di Reggio Calabria
ADDRESS: Via T. Campanella
CITY: Catanzaro
POSTAL CODE: 88100
TELEPHONE: 0961-7123-22, 23, 24
FAX: 0961-774424
E-MAIL: desarro@the
brain.net
PUBLICATIONS:
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DE SARRO G.B., BAGETTA G., SPAGNOLO C., NISTICO' G. Antagonists of
N-methyl-D-aspartate receptors block seizures induced by putrescine into
the deep prepiriform cortex. Neuropharmacol. 32: 43-50, 1993.
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DE SARRO G.B., DE SARRO A. Anticonvulsant properties of non-competitive
antagonists of NMDA receptor in genetically epilepsy prone rats. Comparison
with CPPene. Neuropharmacol. 32: 51-58, 1993.
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DE SARRO G.B., DONATO DI PAOLA E., DE SARRO A., VIDAL M.J. L-Arginine potentiates
excitatory amino acid-induced seizures elicited in the deep prepiriform cortex.
Eur. J. Pharmacol. 230: 151-158, 1993.
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DE SARRO A., ZAPPALą M., CHIMIRRI A., GRASSO S., DE SARRO G.B. Quinolones
potentiate cefazolin-induced seizures in DBA/2 mice. Antim. Age.
Chemother. 37: 1497-1503, 1993.
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DE SARRO G.B., ONGINI E., BERTORELLI R., AGUGLIA U., DE SARRO A. Excitatory
amino acid neurotransmission through both NMDA and non-NMDA receptors is
involved in the anticonvulsant activity of felbamate in DBA/2 mice. Eur.
J. Pharmacol. 262: 11-19, 1994.
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DE SARRO A., AMMENDOLA D., ZAPPALą M., GRASSO S., DE SARRO G.B. Structure
and convulsant properties relationship of some b-lactam derivatives following
intracerebroventricular microinjection in rats. Antim. Age. Chemother.,
39: 232-237, 1995.
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DE SARRO G.B., AMMENDOLA D., NAVA F., DE SARRO A. Effects of some excitatory
amino acid antagonists on imipenem-induced seizures in DBA/2 mice. Brain
Res., 671: 131-140, 1995.
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DE SARRO G.B., CHIMIRRI A., DE SARRO A., GITTO R., GRASSO S., GIUSTI P.,
CHAPMAN A.G. GYKI 52466 and related 2,3-benzodiazepines as anticonvulsant
agents in DBA/2 mice. Eur. J. Pharmacol. 294: 411-422, 1995.
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DE SARRO G.B., NAVA F., AGUGLIA U., DE SARRO A. Lamotrigine potentiates the
antiseizure activity of some anticonvulsants in DBA/2 mice.
Neuropharmacology 35: 153-158, 1996.
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DE SARRO G.B., DE SARRO A., AMMENDOLA D, PATEL S. Lack of development of
tolerance to anticonvulsant activity of CGP 37849 and CGP 39551 in genetically
epilepsy-prone rats. Brain Res. 692: 11-19, 1996.
RESEARCH GROUP MEMBERS:
-
De Pasquale Anna, P.O.
-
Saija Antonella, R.U.
-
Rapisarda Antonio, R.U.
-
Trombetta Domenico, B.PDR.
-
Tomaino Antonio, B.
AFFILIATION:
Dipartimento Farmaco-Biologico
Settore di Farmacologia
Facoltą di Farmacia, Universitą di Messina
ADDRESS: Contrada Annunziata
CITY: Messina
POSTAL CODE: 98168
TELEPHONE: 090/358178-6766530
FAX: 090/355703
PUBLICATIONS:
-
RAPISARDA, A., RAGUSA , S. AND DE PASQUALE, A. Hepatotoxic effect of the
leaves of some Cordia species. Acta Horticolturae. 332: 237-42, 1993.
-
SAIJA, A., PRINCI, P., CASUSCELLI, F., LANZA, M., SCALESE, M., TROMBETTA,
D., COSTA, G. AND DE SARRO, G.B. Genetically epilepsy-prone rodents show
some changes of ion levels in the brain. Brain Res. Bull. 33: 1-6,
1994.
-
SAIJA, A., PRINCI, P., PISANI, A., LANZA, M., SCALESE, M., ARAMNEJAD, E.,
CESERANI, R. AND COSTA, G. Protective effects of glutathione on kainic
acid-induced neuropathological changes in the rat brain. Gen.
Pharmacol.. 25: 97-102, 1994.
-
TRIMARCHI, G.R., IMPERATORE, C., ARCADI, F.A., SAIJA, A., DE SARRO, A., DE
SARRO, G.B. AND COSTA G. Increased cardiovascular responsiveness to central
cholinergic stimulation in the genetically epilepsy-prone rat. J. Pharm.
Pharmacol. 46: 497-502, 1994.
-
SAIJA, A., PRINCI, P., LANZA, M., SCALESE, M., ARAMNEJAD, E. AND DE SARRO
A. Systemic cytokine administration can affect blood-brain barrier permeability
in the rat. Life Sci. 56: 775-84, 1995.
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SAIJA, A., SCALESE, M., LANZA, M., MARZULLO, D., BONINA, F. AND CASTELLI,
F. Flavonoids as antioxidant agents: importance of their interaction with
biomembranes. Free Radicals in Biology and Medicine. 19: 481-486,
1995.
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SAIJA, A., BONINA, F., TROMBETTA, D., TOMAINO, A., MONTENEGRO, L., SMERIGLIO,
P., CASTELLI, F. Flavonoid-biomembrane interactions: a calorimetric study
on dipalmitoylphosphatidylcholine vesicles. Int. J. Pharmaceut. 124:
1-8, 1995.
-
BONINA, F., LANZA, M., MONTENEGRO, L., SALERNO, L., SMERIGLIO, P., TROMBETTA,
D. AND SAIJA, A. Transport of alpha-tocopherol and its derivatives through
erythrocyte membranes. Pharmaceut. Res. 13: 1342-6, 1996.
-
SAIJA, A., RAPISARDA, A., TOMAINO, A., TROMBETTA, D. AND DE FEO, G. Flavonoid
interactions with biomembranes. Phytother. Res. In press, 1996.
-
BONINA, F., LANZA, M., MONTENEGRO, L., PUGLISI, C., TOMAINO, A., TROMBETTA,
D., CASTELLI, F. AND SAIJA, A. Flavonoids as potential protective agents
against photooxidative skin damages. Int. J. Pharmaceut. In press,
1996.
RESEARCH GROUP MEMBERS:
-
Del Zompo Maria, P.A.
-
Bocchetta Alberto, T.L.
-
Piccardi Maria Paola, T.L.
-
Ruiu Stefania, D.DR.
AFFILIATION:
Dipartimento di Neuroscienze "B.B. Brodie"
Facoltą di Medicina e Chirurgia
Universitą di Cagliari
ADDRESS: Via Porcell, 4
CITY: Cagliari
POSTAL CODE: 09124
TELEPHONE: 070 - 6092438
FAX: 070 - 669242
E-MAIL: delzompo@unica.it
PUBLICATIONS:
-
DEL ZOMPO, M., PICCARDI, M.P., RUIU, S., QUARTU, M., GESSA, G.L., ANS VACCARI,
A. Selective MPP+ uptake into synaptic dopamine vesicles: possible involvement
of MPTP neurotossicity. Brit. J. Pharmacol. 109: 411-414, 1993.
-
BOCCHETTA, A., BERNARDI, F., BURRAI, C., PEDDITZI, M., AND DEL ZOMPO, M.
A double-blind study of L-sulpiride versus amitryptiline in lithium-maintained
bipolar depressives. Acta Psychiatrica Scandinavica 88: 434-439, 1993.
-
DEL ZOMPO, M., LAI, M., LOI, V., AND PISANO, M.R. Dopamine hypersensitivity
in migraine: role of apomorphine syncope. Headache 35: 222-224, 1995.
-
DEL ZOMPO M., BOCCHETTA A., LOVISELLI A., MARTINO E., POST R.M., AND KETTER
T.A. Thyroid function during carbamazepine. Biol. Psych. 36 :
135-136, 1994.
-
BOCCHETTA, A., CHERCHI, A., LOVISELLI, A., MOSSA, P., VELLUZZI, F., DERAI,
R, AND DEL ZOMPO, M. Six-year follow-up of thyroid function during lithium
treatment. Acta Psychiatrica Scandinavica 94: 45-48, 1996
RESEARCH GROUP MEMBERS :
-
Della Corte Laura, P.A.
-
Colivicchi Alessandra, D.DR.
-
Bianchi Loria, B.PDR.
-
Galeffi Francesca, B.
-
Bartolini Petra, B.
AFFILIATION :
Dipartimento di Farmacologia Preclinica e Clinica M. Aiazzi Mancini
Universitą di Firenze
ADDRESS: Viale Morgagni, 65
CITY: Firenze
POSTAL CODE: 50134
TELEPHONE: 055-4237411, 412, 440, 454, 456
FAX: 055-4361613
E-MAIL: d-corte@stat.ds.unifi.it
PUBLICATIONS:
-
DELLA CORTE, L., VALOTI, M., PALMI, M., GIOVANNINI, M.G. AND SGARAGLI, G.P.
Pharmacokinetics of chlorimipramine, chlorpromazine and their N-dealkylated
metabolites in plasma of healthy volunteers after a single oral dose of the
parent compounds. J. Pharm. Pharmacol. 45: 825-829, 1993.
-
DELLA CORTE, L., BIANCHI, L., COLIVICCHI, A. AND TIPTON, K.F. The effect
of ethanol on rat brain monoamine oxidase activities. J. Neural
Transmission, 41: 51-55, 1994.
-
BIANCHI, L., SHARP, T., BOLAM, J.P. AND DELLA CORTE, L. The effect of kainic
acid on the release of GABA in rat neostriatum and substantia nigra.
Neuroreport: 5, 1233-1236, 1994.
-
SGARAGLI, G.P., FROSINI, M., PALMI, M., BIANCHI, L. AND DELLA CORTE,
L. Calcium and taurine interaction in mammalian brain metabolism. Adv
Exp Med Biol 359: 299-308, 1994.
-
GIOVANNINI, M.G., MUTOLO, D., BIANCHI, L., MICHELASSI, A. AND PEPEU,
G. NMDA receptor antagonists decrease GABA outflow from the septum
and increase acetylcholine outflow from the hippocampus: a microdialysis
study. J. Neurosci. 14: 1358-1365, 1994.
-
SGARAGLI, G.P., VALOTI, M., PALMI, M., FROSINI, M., GIOVANNINI, M.G., BIANCHI,
L. DELLA CORTE, L. Rat tissue concentrations of chlorimipramine,
chlorpromazine and their N-demethylated metabolites after a single oral dose
of the parent compounds. J. Pharm. Pharmacol. 47: 782-790, 1995.
-
BIANCHI, L., COLIVICCHI, M.A. AND DELLA CORTE, L., VALOTI, M., SGARAGLI,
G.P. AND BECHI, P. Measurement of synthetic phenolic antioxidants in human
tissues by High-Performance Liquid Chromatography with coulometric
electrochemical detection. J. Chromatogr., In press, 1996.
-
CORSI, C., PAZZAGLI, M., BIANCHI, L., DELLA CORTE, L., PEPEU, G. AND PEDATA,
F. Excitatory amino acids and GABA release from the striatum of aging rats:
adenosine modulation. Neurobiol. Aging, In press, 1996.
RESEARCH GROUP MEMBERS:
-
Desole M.Speranza, P.A.
-
Fresu Luigia, R.U.
-
Sciola Luigi, R.U.
-
Piras Giovanna, D.DR.
-
Migheli Rossana, D.DR.
-
Delogu M.Rosaria, D.DR.
-
Sircana Sara, D.DR.
-
Zangani Danilo, D.DR.
AFFILIATION:
Istituto di Farmacologia
Facoltą di Medicina e Chirurgia
Universitą di Sassari
ADDRESS: Viale S.Pietro 43B
CITY: Sassari
POSTAL CODE: 07100
TELEPHONE: 079-228519
FAX: 079-228525
E-MAIL: desole@ssmain.uniss.it
PUBLICATIONS:
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DESOLE M.S.,ESPOSITO G.,ENRICO P.,MIELE M.,FRESU L.,DE NATALE MIELE E. AND
GRELLA G. Effects of ageing on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP) neurotoxic effects on striatum and brainstem in the rat. Neurosci.
Lett. 159:143-146, 1993.
-
DESOLE M.S.,ESPOSITO G.,FRESU L.,MIGHELI R., ENRICO P.,MIELE M.,DE NATALE
G. AND MIELE E. Correlation between 1-methyl-4-phenylpyridinium ion (MPP+)
levels, ascorbic acid oxidation and glutathione levels in the striatal
synaptosomes of the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated
rat. Neurosci. Lett. 161: 121-123,1993.
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BRACOLLA A., SHIN C.-K., ROSE M.J., PIRAS G., WARREN T.C., GRYGON C.A., INGRAHAM
R.H., GREENWOOD D.J., COUSIN R.C., RICHMAN D., CHENG Y.-C. AND GRIFFIN J.A.
Amino acid substitutions in HIV-reverse transcritase with corresponding residues
from HIV-2: effect on kinetic constants and inhibition by nonnucleoside
analogs. Biol. Chem. 268: 16571-16577, 1993
-
DESOLE M.S., KIM W.-K., RABIN R.A. AND LAYCHOCK S.G. Nitric oxide reduces
depolarization-induced calcium mobilization in PC12 vells by a cyclic
GMP-mediated mechanism. Neuropharmacology 33: 193-198, 1994.
-
DESOLE M.S., MIELE M., ESPOSITO G., MIGHELI R., FRESU L., DE NATALE G. AND
MIELE E. Dopaminergic system activity and cellular defense mechanisms in
the striatum and striatal synaptosomes of the rat subchronically exposed
to manganese. Arch. Toxicol. 68: 566-570, 1994.
-
DESOLE M.S., MIELE M., ESPOSITO G., MIGHEL R., FRESU L., ENRICO P., DE NATALE
G. AND MIELE E. Monoaminergic systems activity and cellular defense mechanisms
in the brainstem of young and aged rats subchronically exposed to manganese.
Neurosci. Lett. 177: 71-74, 1994.
-
DESOLE M.S.,ESPOSITO G.,MIGHELI R., FRESU L., SIRCANA S., ZANGANI D., MIELE
M. AND MIELE E. Cellular defense mecanisms in the striatum of young and aged
rats subchronically exposed to manganese. Neuropharmacology
34:289-295,1995.
-
PIRAS G., DUTSCHMAN G.E., IM G.J., PAN B.C., CHU S.H. AND CHENG Y.C. The
action of uracil analogues of human imunodeficiency virus type 1 (HIV-1)
and its reverse transcriptase. Antimicrob. Agents. Chemother. 39:
539-541, 1995.
-
DESOLE M.S., ESPOSITO G., FRESU L.G., MIGHELI R., SIRCANA S., DELOGU P. M.
R., MIELE M. AND MIELE E. Further investigation of allopurinol effects on
MPTP-induced oxidative stress in the striatum and brainstem of the rat.
Pharmacol. Biochem. Behav. 54:377-383,1996.
-
DESOLE M.S., SCIOLA L., DELOGU M.R., SIRCANA S. AND MIGHELI R. Manganese
and 1-methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine induce apoptosis
in PC12 cells. Neurosci. Lett. 209:193-196,1996.
RESEARCH GROUP MEMBERS:
-
Di Renzo Gianfranco, P.O.
-
Canzoniero Lorella, B.P.D:R.
-
Caporaso Roberta, B
AFFILIATION:
Facoltą di Farmacia
Universitą degli Studi di Reggio Calabria
ADDRESS: Complesso Ninģ Barbieri
CITY: Roccelletta di Borgia (CZ)
POSTAL CODE: 88021
TELEPHONE: 0961-391157
FAX: 0961-391490
PUBLICATIONS:
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AMOROSO S., SENSI S., DI RENZO G.F. AND ANNUNZIATO L.The inhibition of tha
Na+-Ca2+ exchanger enhances anoxia and glucopenia-induced 3H aspartate release
in hippocampal slices. J. Pharmacol. Exp. Ther. 264:515-529,1993.
-
CANZONIERO L.M.T., TAGLIALATELA M., DI RENZO,G.F. AND ANNUNZIATO L.:Gadolinium
and Neomycin block voltage-sensitive Ca2+ channels without interfering with
the Na+-Ca2+ antiporter in brain nerve endings.Eur. J. Pharmacol.; Molecular
Pharmacology Section. 245: 97-103,1003.
-
CSERNANSKY C.A., CANZONIERO L.M.T., SENSI S., YU S.P. AND CHOI D.W.Delayed
application of Aurintricarboxylic acid reduced glutamate neurotoxicity.
J. Neurosci. Res. 38: 101-108,1994.
-
FATATIS A., CAPORASO R., IANNOTTI E., BASSI A., DI RENZO G.F. AND ANNUNZIATO
L.Relationship between time of activation of Phospholipase C.linked plasma
membrane receptors and reloading of intracellular Ca2+ stores in LAN-1 human
neuroblastoma cells. J. Biol. Chem. 269:18021-18027,1994.
-
LYNCH J.J., YU S.P., CANZONIERO L.M.T., SENSI S. AND CHOI D.W- Sodium channels
blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury
when combined with glutamate receptor antagonists. J. Pharmacol. Exp.
Ther. 273: 554-560,1995.
-
DUGAN.L.L., SENSI S., CANZONIERO L.M.T., HANDRAN S.H., ROTHMAN S.M, GOLDBERG
M.P. AND CHOI D.W. Mitochondrial production of reactive oxygen species in
cortical neurons following exposure to N-methyl-Daspartate. J.
Neurosci.:15:6377-6388, 1995.
-
DI RENZO G.F., AMOROSO S., BASSI A., FATATIS A., CATALDI M., COLAO A.M.,
LOMBARDI G. AND ANNUNZIATO L.Role of the Na+-Ca2+ and Na+-H+ antiporters
in prolactin release from anterior pituitary cells in primary culture. Eur.
J. Pharmacol. 204:11-15, 1995.
-
AMOROSO S., IANNOTTI E., SAGGESE M.L., DI RENZO G.F. AND ANNUNZIATO L. The
A1 agonist CCPA reduced bisoxonol-monitored membrane potential depolarization
elicited by high K+ in cerebrocortical nerve endings. Biochim. Biophys.
Acta. 1239:67-73.1995.
-
CANZONIERO L.M.T., SENSI S, AND CHOI D.W. Recovery from NMDA-induced
intracellular acidification is slow and dependent on extracellular bicarbonate.
Amer. J. Physiol. 270:C593-C599,1996.
-
AMOROSO S., DE MEIO M., RUSSO G.M., BASSI A., MENTAGNANI S., DI RENZO G.F.,
AND ANNUNZIATO L. The Na+-Ca2+ exchanger operates as a Na+ efflux and Ca2+
influx pathway during in vitro ischemia in C6 glioma cells. Brit. J.
Pharmacol. In press, 1996.
RESEARCH GROUP MEMBERS:
-
Drago Filippo, P.A.
-
Villareale Giuseppe, D.DR.
-
Marino Vittorio, D.DR.
-
D'Agata Velia, B.
-
Di Leo Francesco, B.
-
Busą Lina, B.
AFFILIATION:
Istituto di Farmacologia
Facoltą di Medicina e Chirurgia
Universitą degli Studi di Catania
ADDRESS: Viale A. Doria, 6
CITY: Catania
POSTAL CODE: 95125
TELEPHONE: 095-330709, 330533 (int. 264)
FAX: 095-333219
E-MAIL: fdrago@mbox.vol.it
PUBLICATIONS:
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D'AGATA, V., AND DRAGO F., SERAPIDE F., CICIRATA F. Effects of cerebellectomy
on motivation-related behavior: a time-course study. Physiol. Behav.
53: 173-176, 1993.
-
DRAGO, F., MAUCERI F., NARDO L., VALERIO C., GENAZZANI A.A., AND GRASSI M.
Effects of cytidine-diphosphocholine on acetylcholine-mediated behaviors
in the rat. Brain Res. Bull. 31: 485-489, 1993.
-
GRASSI, M., AND DRAGO F. Effects of oxytocin on emotional stress and
strees-induced gastric lesions. J. Physiol. 87: 261-264, 1993.
-
DRAGO, F., GRASSI M., AND GENAZZANI A.A. Neuromediators in aging and gastric
mucosal injury. J. Physiol. 87: 379-383, 1993.
-
DRAGO, F., DAL BELLO A., MARINO V., PISATI R., LODOLA E., AND BARBIERI P.
Evaluation of the effects of thymoxamine solution 0.5% on mydriasis induced
by ibopamine solution 1%. Eur. J. Clin. Pharmacol. 44: 477-480, 1993.
-
DRAGO, F., COPPI G., ANTONUZZO P.A., VALERIO C., GENAZZANI A.A., GRASSI M.,
RAFFAELE R., AND SCAPAGNINI U. Effects of RGH 2202 on cognitive and motor
behavior of the rat. Neurobiol. Aging 17: 67-71, 1996.
-
DRAGO, F., MUSCO S., NARDO L., VALERIO C., GRASSI M., AND RAMPELLO L. Behavioral
and neurochemical alterations induced by reversible conductive hearing loss
in aged male rats. Neurosci. Lett. 205: 1-4, 1996.
-
DRAGO, F., DI LEO F., IKONOMOU S., ANZALLO C., BUSą L., AND LO PRESTI
L. Behavioral and endocrine effects of growth hormone administration in aged
female rats. Psychoneuroendocrinology 21: 401-410, 1996.
-
DRAGO, F., NARDO L., RAMPELLO L., AND RAFFAELE R. Vestibular compensation
in aged rats with unilateral labyrinthectomy treated with dopaminergic drugs.
Pharmacol. Res. 33: 135-140, 1996.
-
CLEMENTI, G., VALERIO C., EMMI I., PRATO A., AND DRAGO F. Behavioral effects
of amylin injected intracerebroventricularly in the rat. Peptides
17: 324-326, 1996.
RESEARCH GROUP MEMBERS:
-
Ferrari Francesca, P.O.
-
Giuliani Daniela, D. DR.
AFFILIATION:
Sezione di Farmacologia
Dipt. di Scienze Biomediche
Universitą di Modena
ADDRESS: Via G. Campi, 287
CITY: Modena
POSTAL CODE: 41100
TELEPHONE: 0039-59-428419
FAX: 0039-59-372653
E-MAIL: farmacol@.unimo.it
PUBLICATIONS:
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FERRARI F., PELLONI F. AND GIULIANI D. Behavioural profile in chicken of
CQ 32-084 and CQP 201-403, two dopamine agonists. Pharmacol. Biochem.
Behav. 45: 117-122, 1993.
-
FERRARI F. AND GIULIANI D.: Behavioural effects induced in rats and chicks
by D2 dopamine agonists. Physiol. Behav. 54: 695-700, 1993.
-
FERRARI F., PELLONI F. AND GIULIANI D. Behavioural evidence that different
neurochemical mechanisms underly stretching-yawning and penile erection induced
in male rats by SND 919, a new selective D2 dopamine receptor agonist.
Psychopharmacology, 113: 172-176, 1993.
-
FERRARI F. AND GIULIANI D. Influence of idazoxan on the dopamine D2 receptor
agonist-induced behavioural effects in rats. Eur. J. Pharmacol. 250:
51-57, 1993.
-
FERRARI F. AND GIULIANI D. The selective D2 dopamine receptor antagonist
(-)eticlopride counteracts the ejaculatio preacox induced by the selective
D2 dopamine agonist SND 919 in the rat. Life Sci. 55: 1155-1162, 1994.
-
FERRARI F. AND GIULIANI D. Sexual attraction and copulation in male rats:
effects of the dopamine agonist SND 919. Pharmacol. Biochem. Behav.
50: 29-34, 1995.
-
FERRARI F. AND GIULIANI D.: Effect on rat feeding behavior of two selective
D2 dopamine agonists. Physiology and Behav. 56:921-926, 1995.
-
FERRARI F. AND GIULIANI D.: Influence of Eticlopride on cocaine- and DA D2
agonist-induced behavioral effects in rats. Pharmacol. Biochem. Behav.
53: 525-530, 1996.
-
FERRARI F. AND GIULIANI D.: Behavioral effects induced by the dopamine D3
agonist 7-OH-DPAT in sexually-active and inactive male rats.
Neuropharmacology 35: 279-284, 1996 .
-
GIULIANI D. AND FERRARI F. Differential behavioral response to dopamine D2
agonists by sexually naive, sexually active and sexually inactive male rats.
Behav. Neurosci. 110 : In press, 1996.
RESEARCH GROUP MEMBERS:
-
Ferri Sergio, P.O.
-
Candeletti Sanzio, T.L.
-
Romualdi Patrizia, R.U.
-
Lesa Giovanni, T.L.
-
Donatini Alessandra, D.DR.
AFFILIATION:
Dipartimento di Farmacologia
Facoltą di Farmacia
Universitą degli Studi di Bologna
ADDRESS: Via Irnerio, 48
CITY: Bologna
POSTAL CODE: 40126
TELEPHONE: 051 - 242025 / 243101
FAX: 051 - 248862
E-MAIL: ferri@biocfarm.unibo.it
PUBLICATIONS:
-
MELCHIORRE, C., ROMUALDI, P., BOLOGNESI, M.L., DONATINI, A., FERRI, S. Binding
profile of benextramine at neuropeptide Y receptor subtypes in rat brain
areas. Eur. J. Pharmacol.. 265: 93-98, 1994.
-
AROIAN, R.V., LESA, G., STERNBERG, P.W. Mutations in the Caenorhabditis elegans
let-23 EGFR-like gene define elements important for cell-type specificity
and function. EMBO J. 13: 360-366, 1994.
-
CANDELETTI, S., FERRI, S. Cerebrospinal alterations of immunoreactive dynorphin
A after unilateral rhizotomy in the rat. Brain Res.. 670: 289-296,
1995.
-
ROMUALDI, P., LESA, G., DONATINI, A., FERRI, S. Long-term exposure to opioid
antagonists up-regulates prodynorphin gene expression in rat brain. Brain
Res.. 672: 42-47, 1995.
-
ROMUALDI, P., DONATINI, A., BREGOLA, G. BIANCHI, C., BEANI, L., FERRI, S.,
SIMONATO, M. Early changes in prodynorphin mRNA and ir-dynorphin A levels
after kindled seizures in the rat. Eur. J. Neurosci. 7: 171-177, 1995.
-
ROMUALDI, P., DONATINI, A., FERRI, S. Prodynorphin gene expression regulation
by chronic methamphetamine in rat brain. Analgesia, 1: 679-682, 1995.
-
STERNBERG, P.W., LESA, G., LEE, J.H., KATZ, W.S., YOON, C., CLANDININ, T.R.,
HUANG, L.S., CHAMBERLIN, H.M., JONGEWARD, G. LET-23 -mediated signal transduction
during Caenorhabditis elegans development. Mol. Reprod. Develop..
42: 523-528, 1995.
-
ROMUALDI, P., DONATINI, A., IZENWASSER, S., COX, B.M., FERRI, S. Chronic
intracerebroventricular cocaine differentially affects prodynorphin gene
expression in rat hypothalamus and caudate-putamen. Mol. Brain Res..
40: 153-156, 1996.
-
SIMONATO, M., BREGOLA, G., DONATINI, A., BIANCHI, C., BEANI, L., FERRI, S.,
ROMUALDI, P. Kindled seizure-induced c-Fos and prodynorphin mRNA expressions
are unrelated in the rat brain. Eur. J. Neurosci. 16: In press, 1996.
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