SIF - Societą
Italiana di Farmacologia
"SIF - La Ricerca Farmacologica in Italia"
GASTROINTESTINAL PHARMACOLOGY
RESEARCH GROUP MEMBERS:
-
Bertaccini Giulio, P.O.
-
Coruzzi Gabriella, P.A.
-
Scarpignato Carmelo, P.A.
-
Poli Enzo, P.A.
-
Morini Giuseppina, R.U.
-
Adami Maristella, R.U.
-
Pozzoli Cristina, R.U.
-
Gambarelli Enrica, D.DR.
-
Coppelli Gabriella, B.
AFFILIATION:
Istituto di Farmacologia
Facoltą di Medicina e Chirurgia
Universitą degli Studi di Parma
ADDRESS: Via Gramsci, 14, Ospedale Maggiore
CITY: Parma
POSTAL CODE: 43100
TELEPHONE: 0521-290-383, 384, 381
FAX: 0521-294-089
PUBLICATIONS:
-
CORUZZI G., TIMMERMAN H., ADAMI M. AND BERTACCINI G. The new potent and selective
histamine H2 receptor agonist amthamine as a tool to study gastric secretion.
Naunyn-Schmied. Arch. Pharmacol. 348: 77-81,1993.
-
POLI E., POZZOLI C., CORUZZI G. AND BERTACCINI G. Histamine H3-receptor-induced
inhibition of duodenal cholinergic transmission is independent of intracellular
cyclic AMP and GMP. General Pharmacol. 24: 1273-1278, 1993.
-
SOLDANI G., MENGOZZI G., INTORRE L., DE GIORGI G., CORUZZI G. AND BERTACCINI
G. Histamine H3 receptor-mediated inhibition of gastric acid secretion in
conscious dogs. Naunyn-Schmied. Arch. Pharmacol. 347: 61-65, 1993.
-
POLI E., TODOROV S., POZZOLI C. AND BERTACCINI G. Presynaptic histamine H2
receptors modulate the sympathetic nerve transmission in the isolated rat
vas deferens; no role for H3-receptors. Agents Actions. 42: 95-100,
1994.
-
POLI E., POZZOLI C., CORUZZI G. AND BERTACCINI G. Signal transducing mechanisms
coupled to histamine H3 receptors and alpha-2 adrenoceptors in the guinea
pig duodenum: possible involvement of N-type Ca++ channels. J.
Pharmacol. Exp. Ther.. 270: 788-794, 1994.
-
CORUZZI G., GAMBARELLI E., BERTACCINI G. AND TIMMERMAN H. Cardiovascular
effects of selective agonists and antagonists of histamine H3 receptors in
the anaesthetized rat. Naunyn-Schmied. Arch. Pharmacol. 351: 569-575,
1995.
-
MORINI G., GRANDI D. AND BERTACCINI G. (R)-alpha-methylhistamine inhibits
ethanol-induced gastric lesions in the rat: involvement of histamine H3
receptors?. Digestion 56: 145-152, 1995.
-
BERTACCINI G. AND CORUZZI G. An update on histamine H3 receptors and
gastrointestinal functions. Digestive Diseases and Sciences 40: 2052-2063,
1995.
-
MORINI G., GRANDI D., ARCARI M.L. AND BERTACCINI G. Indomethacin-induced
morpholigical changes in the rat gastric mucosa, with or without prior treatment
with two proton pump inhibitors. Alimen. Pharmacol. Therap. 9: 615-623,
1995.
-
CORUZZI G., ADAMI M., POZZOLI C., GIORGI F. AND BERTACCINI G. Cardiac and
gastric effects of histamine H2 receptor antagonists: no evidence for a
correlation between lipophilicity and receptor affinity. Brit. J.
Pharmacol.. 118: 1813-1821, 1996.
RESEARCH GROUP MEMBERS:
-
Capasso Francesco, P.O.
-
Mascolo Nicola, R.U.
-
Di Carlo Giulia, B.PDR
-
Izzo Angelo A., B.PDR
-
Borrelli Francesca, B.
AFFILIATION:
Dipartimento di Farmacologia Sperimentale
Facoltą di Farmacia
Universitą di Napoli Federico II
ADDRESS: Via D. Montesano 49
CITY: Napoli
POSTAL CODE: 80131
TELEPHONE: 081-7486415-432-436-439
FAX: 081-7486403
PUBLICATIONS:
-
MASCOLO N., IZZO A.A., BARBATO F., CAPASSO F. Inhibitors of nitric oxide
synthase prevent castor-oil induced diarrhoea in rats. Brit. J.
Pharmacol. 108 : 861-864, 1993.
-
MASCOLO N., IZZO A.A., AUTORE G., BARBATO F., CAPASSO F. Nitric oxide and
castor oil induced diarrhoea. J. Pharmacol. Exp. Ther. 268 :
291-295, 1994.
-
IZZO A.A., GAGINELLA T.S., MASCOLO N., CAPASSO F. Nitric oxide is a mediator
of the laxative action of magnesium sulphate. Brit. J. Pharmacol.
113 : 228-232, 1994.
-
GAGINELLA T.S., MASCOLO N., IZZO A.A., AUTORE G., CAPASSO F. Nitric oxide
is a mediator of bisacodyl and phenolphtalein laxative action: induction
of nitric oxide synthase. J. Pharmacol. Exp. Ther. 270 : 1239-1245,
1994.
-
MASCOLO N., GAGINELLA T.S., IZZO A.A., DI CARLO G., CAPASSO F. Nitric oxide
involvement in sodium choleate -induced fluid secretion and diarrhoea in
rats. Eur. J. Pharmacol. 264 : 21-26, 1994.
-
CAPASSO F., MASCOLO N., IZZO A.A., GAGINELLA T.S. Dissociation of castor-
oil-induced diarrhoea and intestinal mucosal injury in rat:effect of
NG-nitro-L-arginine methyl ester Brit. J. Pharmacol.
113 :1127-1130, 1994
-
IZZO A.A., GAGINELLA T.S., MASCOLO N., CAPASSO F. L-NAME modulates intestinal
secretion and motility produced by carbachol. Eur. J. Pharmacol.
271 : 31-35,1994
-
MASCOLO N., IZZO A.A., AUTORE G., MAIELLO F.M., DI CARLO G., CAPASSO F. Acetic
acid-induced colitis in normal and EFAD rats. J. Pharmacol. Exp. Ther.
272 : 469-475,1995
-
IZZO A.A., GAGINELLA T.S., MASCOLO N., BORRELLI F., CAPASSO F.
NG-nitro-L-arginine methyl ester reduces senna-and cascara-induced
diarrhoea and fluid secretion in the rat. Eur. J. Pharmacol. 301 :
137-142, 1996.
-
MASCOLO N., IZZO A.A., GAGINELLA T.S., CAPASSO F. Relationship between
platelet-activating factor and nitric oxide in castor oil-induced damage
in the rat duodenum. Naunyn-Schied. Arch. Pharmacol. 353 : 680-684,
1996
RESEARCH GROUP MEMBERS:
-
Carganico Germano, Dir. Ricerca &
Sviluppo
-
Maggi Carlo Alberto, Dir. Discovery
-
Giachetti Antonio, Dir. Sviluppo
-
Evangelista Stefano, Sviluppo Preclinico
-
Subissi Alessandro, Progetti esterni
-
Furio Martino, Pianificazione
-
Criscuoli Marco, Resp. Dip. Farmacol. Firenze
-
Giuliani Sandro, C. L.
-
Renzetti Anna Rita, C. L.
-
Santicioli Paolo, C. L.
-
Catalioto Rose-Marie, R. I.
-
Cucchi Paola, R. I.
-
Lecci Alessandro, R. I.
-
Lippi Annalisa, R. I.
-
Meini Stefania, R. I.
-
Patacchini Riccardo, R. I.
-
Tramontana Manuela, R. I.
-
Manzini Stefano, Resp. Dip. Farmacol. Pomezia
-
Cirillo Rocco,
C.L
-
Iafrate Elisabetta, C.L.
-
Palma Carla,
C.L.
-
Astolfi Mara,
R.I.
-
Bellarosa Daniela,
R.I.
-
Bigioni Mario,
R.I.
-
Ciucci Alessandra, R.I.
-
Conte Bruno, RI.
-
Cutrufo Corrado,
R.I.
-
Parlani Massimo, R.I.
-
Sacco Giuseppe, R.I.
-
Salvatore Carmela, R.I.
-
Crea Attilio, Resp. Dip. Farmacocinetica
& Metabolismo
-
Urso Renato, Resp. Dip.
Farmacocinetica
-
Agostara Giuseppina, R.
I.
AFFILIATION:
Menarini Ricerche S.p.A.
ADDRESS: Via Tito Speri 10, 00040 Pomezia (Roma)
Research and Development: Via Sette Santi 1, 50131 Firenze,
TEL: 055/56801
FAX: 055/5680510
Labs. Florence: Via Rismondo SNC, 50131 Firenze,
Mailing Address:Via sette Santi 3, 50131 Firenze
TEL: 055/56801 FAX: 055/5680419
Labs. Pomezia: Via Tito Speri 10, 00040 Pomezia (Roma),
TEL: 06/911841
FAX: 06/9100220
PUBLICATIONS:
-
GIULIANI, S., LECCI, A., GIACHETTI, A., AND MAGGI, C.A. Tachykinins and reflexly
evoked atropine-resistant motility in the guinea-pig colon in vivo. J.
Pharmacol. Exp. Ther. 265: 1224-1231, 1993.
-
MAGGI C.A., PATACCHINI R., MEINI S., QUARTARA L., SISTO A., POTIER E., GIULIANI
S., AND GIACHETTI A. Comparison of tachykinin NK1 and NK2 receptors in the
circular muscle of the guinea-pig ileum and proximal colon. Brit. J.
Pharmacol. 112:150-160, 1994.
-
SANTICIOLI, P., AND MAGGI ,C.A. Inhibitory transmitter action of calcitonin
gene-related peptide in guinea-pig ureter via activation of
glibenclamide-sensitive K channels. Brit. J. Pharmacol. 113: 588-592,
1994.
-
TRAMONTANA, M., RENZI, D., CALABRO', A., PANERAI, C., MILANI, S., SURRENTI,
C., EVANGELISTA, S. Influence of capsaicin-sensitive afferent fibers on acetic
acid-induced chronic gastric ulcers in rats. Sc. J. Gastroenterol.
29: 406-413, 1994.
-
CIRILLO, R., RENZETTI, A.R., CUCCHI, P., GUELFI, M., SALIMBENI, A., CALIARI,
S., CASTELLUCCI, A., EVANGELISTA, S., SUBISSI, A. AND GIACHETTI A. Pharmacology
of LR-B/081, a new highly potent, selective and orally active nonpeptide
angiotensin II AT1 receptor antagonist. Brit. J. Pharmacol. 114:
1117-1124, 1995.
-
GOSO C., ASTOLFI M., PARLANI M. AND MANZINI S. [3 H] [bAla8] neurokin¦n A-(4-10):
a novel, selective radioligand for the tachykinin NK2 receptor. Eur. J.
Pharmacol. 294:239-245, 1995.
-
PALMA, C., URBANI, F., AND MANZINI, S. Interleukin-6 production by U373 MG,
a human astrocytoma cell line: different pathways involved in substance P
and lipopolysaccharide activation. J. Neuroimmunol. 59: 155-163, 1995.
-
CATALIOTO, R-M., RENZETTI, A.R., CRISCUOLI, M., MORBIDELLI, L., AND SUBISSI,
A. Role of calcium in angiotensin II-induced prostaglandin release and DNA
synthesis in rat vascular smooth muscle cells. J. Cardiovasc. Pharmacol.
27: 195-200, 1996.
-
CIUCCI, A., MANZINI, S., LOMBARDI, P., AND ARCAMONE F. Backbone and benzoyl
mustard carrying moiety modifies DNA interaction of distamycin analogues.
Nucl. Acid Res. 24 : 311-315, 1996.
-
CONTE, B., CUTRUFO, C., AND MANZIR¦I,
S. Electrocorticographic desynchronization after application of visceral
and somatic noxious stimuli in urethane anesthetized rats: effect of intratechal
administration of tachykinin (NK1 or NK2) receptor antagonists. J. Pharmacol.
Exp. Ther. 276: 212-218, 1996.
RESEARCH GROUP MEMBERS:
-
Del Tacca Mario, P.O.
-
Danesi Romano, R.U.
-
Blandizzi Corrado, R.U.
-
Di Paolo Antonello, D.DR.
-
Colucci Rocchina, D.DR.
-
Carignani Diego, B.
-
Innocenti Federico, B.
-
Bocci Guido, B.
-
Natale Gianfranco, B.
-
Lazzeri Gloria, B.
-
Nardini Denise, B.
AFFILIATION:
Istituto di Farmacologia
FacoltÆ di Medicina e Chirurgia
Universitą di Pisa
ADDRESS: Via Roma, 55
CITY: Pisa
POSTAL CODE: 56126
TELEPHONE: 050-560109/560509
FAX: 050-551434
E-MAIL: mbxdanesi@mail.cnuce.cnr.it
PUBLICATIONS:
-
DANESI R., DEL BIANCHI S., SOLDANI P., CAMPAGNI A., LA ROCCA R.V., MYERS
C.E., PAPARELLI A., DEL TACCA M.: Suramin inhibits bFGF-induced proliferation
of bovine aortic endothelial cells and angiogenesis in the chick chorioallantoic
membrane. Brit. J. Cancer 68: 932-938, 1993.
-
BLANDIZZI C., TARKOVACS G., NATALE G., DEL TACCA M., VIZI E.S.: Functional
evidence that [3H]acetylcholine and [3H]noradrenaline release from guinea-pig
ileal myenteric plexus and noradrenergic terminals is modulated by different
presynaptic a2-adrenoceptor subtypes. J. Pharmacol. Exp. Ther. 267:
1054-1060, 1993.
-
COSTA M., DANESI R., AGEN C., DI PAOLO A., BASOLO F., DEL BIANCHI S., DEL
TACCA M.: MCF-10A cells infected with the int-2 oncogene induce angiogenesis
in the chick chorioallantoic membrane and in the rat mesentery. Cancer
Res. 54: 9-11, 1994.
-
BLANDIZZI C., GHERARDI G., NATALE G., MARVEGGIO C., DEL TACCA M.: Protective
action of omeprazole against gastric mucosal injury induced by haemorrhagic
shock in rats. Digest. Dis. Sci. 39: 2109-2117, 1994.
-
INNOCENTI F., DANESI R., DI PAOLO A., AGEN C., NARDINI D., BOCCI G., DEL
TACCA M.: Plasma and tissue disposition of taxol in mice. Drug Metab.
Disposition 23: 713-717, 1995.
-
BLANDIZZI C., NATALE G., CARIGNANI D., COLUCCI R., LAZZERI G., DEL TACCA
M.: Central administration of cholecystokinin stimulates gastric pepsinogen
secretion from anaesthetized rats. Neurosci. Lett. 193: 13-16, 1995.
-
BLANDIZZI C., COLUCCI R., CARIGNANI D., NATALE G., LAZZERI G., CREMA F.,
DEL TACCA M.: Role of peripheral GABA-B receptors in the regulation of pepsinogen
secretion in anaesthetized rats. Eur. J. Pharmacol. 294: 191-200,
1995.
-
DANESI R., LA ROCCA R.V., COOPER M.R., RICCIARDI M.P., PELLEGRINI A., KRAGEL
P.J., PAPARELLI A., DEL TACCA M., MYERS C.E.: Clinical and experimental evidence
of inhibition of testosterone production by suramin. J. Clin. Endocrinol.
Metab. 81: 2221-2230, 1996.
-
DANESI R., NARDINI D., BASOLO F., DEL TACCA M., SAMID D., MYERS C.E.:
Phenylacetate inhibits protein isoprenylation and androgen-independent growth
of LNCaP prostate cancer cells transfected with the T24 Ha-ras oncogene.
Mol. Pharmacol. 49: 1329-1337, 1996.
-
COLUCCI R., BLANDIZZI C., CARIGNANI D., LAZZERI G., NATALE G., CREMA F.,
DEL TACCA M.: Determination on functional basis of presynaptic a2-adrenoceptors
subtypes in guinea-pig duodenum. Neurosci. Lett. 210: 29-32, 1996.
RESEARCH GROUP MEMBERS:
-
Franco Luigina, R.U.
-
Doria Denise, B.
AFFILIATION:
Istituto di Farmacologia
Facoltą di Medicina e Chirurgia
Universitą di Verona
ADDRESS: Policlinico di Borgo Roma
CITY: Verona
POSTAL CODE: 37134
TELEPHONE: 045-8098611, 8098604, 8074244
FAX: 045-581111
E-MAIL: luigina@farma.univr.it
PUBLICATIONS:
-
FRANCO, L., ERBETTI, I. AND VELO, G.P. Synthesis of prostaglandin E2 in rat
liver. Pharmacol. Res. 28:367-374, 1993
-
FRANCO, L., MANARA, P., ERBETTI, I. AND VELO, G.P. Anti-ulcer activity of
carbenoxolone and ISF-3401 on PGE2, release in rat gastric mucosa.
Pharmacol. Res. 27:141-150, 1993.
-
CAVALLINI, G., BOVO, P., MARCORI, M., MALTINTI, G., MARCHI, S., COSTA, I.F.,
BELLINI, M., FRANCO, L. AND ANGELINI, G. Effect of sulglycotide on the release
of PGI2 into gastric juice in healthy volunteers. Advances in Therapy
11: 58-61, 1994
-
FRANCO, L. Role of nitric oxide in prevention of ethanol-induced damages
by CuNSN a copper-chelating compound. Inflamm. Res.: 44:27-29, 1995
-
FRANCO, L., CAVALLINI, G., BOVO, P., MARCORI, M., ORLANDI, P.G., MOLTRER,
G., VETTURI, B. AND VELO G.P. Gastric eicosanoid synthesis in normal subjects
and alcoholics after ethanol stimulation. Ital. J. Gastroenterol.
27: 244-247, 1995
-
FRANCO, L. AND VELO, G.P. Eicosanoid and gastroprotectrion by copper derivatives
and NDGA. Inflamm. Res. 44: 139-142, 1995
-
FRANCO, L. AND VELO G.P. A copper-complex reduced gastric damage caused by
acetylsalicylic acid and ethanol. Prostaglandins 51:331-338 1996.
RESEARCH GROUP MEMBERS:
-
Impicciatore Mariannina, P.O.
-
Rescigno Aldo, P.O.
-
Bernini Franco, P.A.
-
Caretta Antonio, P.A.
-
Molina Enzo, P.A.
-
Barocelli Elisabetta, R.U.
-
Chiavarini Milena, R.U.
-
Ballabeni Vigilio, D.DR.
-
Castelli Cristina, D.DR.
AFFILIATION:
Istituto di Farmacologia e Farmacognosia
Facoltą di Farmacia
Universitą degli Studi di Parma
ADDRESS: Viale delle Scienze - Campus Universitario
CITY: Parma
POSTAL CODE: 43100
TELEPHONE: 0521-905090
FAX: 0521-905091
E-MAIL: marimp@IPRUNIV.CCE.UNIPR.IT
PUBLICATIONS:
-
BAROCELLI, E., BALLABENI, V., CARETTA, A., BORDI, F., SILVA, C., MORINI,
G. AND M. IMPICCIATORE Pharmacological profile of new thioperamide derivatives
at histamine peripheral H1-, H2, H3-receptors in guinea-pig. Agents
Actions 38:158-164, 1993.
-
BERNINI, F., DIDONI, G., BELLOSTA, S. AND FUMAGALLI, R. Requirement for
mevalonate in acetylated LDL induction of cholesterol esterification in
macrophages. Atherosclerosis 104: 19-26, 1993
-
BAROCELLI, E., BALLABENI, V., CHIAVARINI, M., MOLINA, E., LAVEZZO, A. AND
IMPICCIATORE, M. Muscarinic M1 and M3 receptor antagonist effects of a new
pirenzepine-analog in isolated guinea-pig ileal longitudinal muscle-myenteric
plexus. Eur. J. Pharmacol. 254:151-157, 1994.
-
BAROCELLI, E., BALLABENI, V., CHIAVARINI, M. AND AND IMPICCIATORE, M.
R-a-methylhistamine-induced inhibition of gastric acid secretion in
pylorus-ligated rats via central histamine H3 receptors. Brit. J.
Pharmacol. 115: 1326-1330, 1995.
-
PLAZZI, P.V., BORDI, F., MOR, M., SILVA, C., MORINI, G., CARETTA, A., BAROCELLI,
E. AND VITALI, T. Heteroarylamines and heteroarylthioethtl imidazoles. Synthesis
and H3-receptor affinity. Eur. J. Med. Chem. 30: 881-889, 1995.
-
BERNINI, F., SCURATI, N., BONFADINI, G. AND FUMAGALLI, G. HMG-CoA reductase
inhibitors reduce acetyl LDL endocytosis in mouse peritoneal macrophages.
Arteriosclerosis, Thromb. Vasc. Biol. 15: 1352-1358, 1995.
-
CARELLI, A., LIBERATORE, F., SCIPIONE, L., IMPICCIATORE, M., BAROCELLI, E.,
CARDELLINI, M. AND GIORGIONI, G.F. New System for the specific delivery and
sustained release of dopamine to the brain. J. Control Release 42:
209-216, 1996
-
BERNINI, F., CALABRESI, L., BONFADINI, G. AND FRANCESCHINI, G. The molecular
structure of apolipoprotein A-II modulates the capacity of HDL to promote
cell cholesterol efflux. Biochim. Biophys. Acta 1299: 103-109, 1996
-
RESCIGNO, A. On absorption rate and fraction absorbed. J. Pharmacokin.
Biopharm. 22: 255-257, 1994
RESEARCH GROUP MEMBERS:
-
Manara Luciano, Dir. R.
-
Aureggi Giulio, C.L.
-
Badone Domenico, C.L.
-
Baroni Marco, C.L.
-
Barzaghi Laura, R.I.
-
Bertario Andrea, R.I.
-
Boccardi Giovanni, Capo Sezione
-
Cardamone Rosanna, R.I.
-
Cecchi Roberto, C.L.
-
Cefalą Antonio, Capo Sezione
-
Croci Tiziano, Capo Sezione
-
Guzzi Umberto, Capo Sezione
-
Ielmini Alessandra, R.I.
-
Landi Marco, C.L.
-
Manzoni Laurenzia, C.L.
-
Marini Pietro, R.I.
-
Miranda Giovanna, Capo Sezione
-
Ottolina Elisabetta, R.I.
AFFILIATION:
Centro Ricerche Sanofi Midy
Sanofi Winthrop S.p.A.
ADDRESS: Via G.B. Piranesi, 38
CITY: Milano
POSTAL CODE: 20137
TELEPHONE: 02 - 7394-1
FAX: 02 - 7394-453
PUBLICATIONS:
-
EMONDS-ALT X., ADVENIER C., CROCI T., MANARA L., NELIAT G., PONCELET M.,
PROIETTO V., SANTUCCI V., SOUBRIE' P., VAN BROECK D., VILAIN P., LE
FUR G., AND BRELIERE J.C. SR 48968, a neurokinin A (NK2) receptor
antagonist. Regul. Peptides. 46: 31-36, 1993.
-
LANDI M., CROCI T., AND MANARA L. Similar atypical ß-adrenergic receptors
mediate in vitro rat adipocyte lipolysis and colonic motility inhibition.
Life Sci. 53: PL 297-302, 1993.
-
FOURNIER J., STEINBERG R., GAUTHIER T., KEANE P.E., GUZZI U., COUDE'
F.X., BOUGAULT I., MAFFRAND J.P., SOUBRIE' P., AND LE FUR G. Protective
effects of SR 57746 in central and peripheral models of neurodegenerative
disorders in rodents and primates. Neuroscience. 55: 629-641, 1993.
-
CROCI T., BASILISCO G., BASSANI A., AND MANARA L. Manometric patterns of
rat colonic motor activity and defecation - Effect of selective 5HT1A agonist
8-OH-DPAT. Digestive Diseases and Sciences. 39: 1968-1973, 1994.
-
CROCI T., EMONDS-ALT X., LE FUR G., AND MANARA L. In vitro characterization
of the non-peptide tachykinin NK1 and NK2-receptor antagonists, SR 140333
and SR 48968 in different rat and guinea-pig intestinal segments.
Life Sci. 56: 267-275, 1995.
-
CROCI T., LANDI M., BIANCHETTI A., AND MANARA L. Drug-induced defaecation
in rats: role of central 5-HT1A receptors. Brit. J. Pharmacol. 115:
203-209, 1995.
-
CROCI T., GIUDICE A., MANARA L., GULLY D., AND LE FUR, G. Promotion by
SR 48692 of gastric emptying and defaecation in rats suggesting a role
of endogenous neurotensin. Brit. J. Pharmacol. 115: 383-384, 1995.
-
CROCI T., LANDI M., EMONDS-ALT X., LE FUR G., AND MANARA L. Neuronal
NK3-receptors in guinea-pig ileum and taenia caeci: in vitro characterization
by their first non-peptide antagonist, SR 142801. Life Sci. 57: PL
361-366, 1995.
-
MANARA L., BADONE D., BARONI M., BOCCARDI G., CECCHI R., CROCI T., GIUDICE
A., GUZZI U., LANDI M., AND LE FUR G. Functional identification of rat atypical
ß-adrenoceptors by the first ß3-selective antagonists,
aryloxypropanolaminotetralins. Brit. J. Pharmacol. 117: 435-442, 1996.
-
DE PONTI F., GIBELLI G., CROCI T., ARCIDIACO M., CREMA F., AND MANARA L.
Functional evidence of atypical ß3-adrenoceptors in the human colon
using the ß3-selective adrenoceptor antagonist, SR 59230A. Brit.
J. Pharmacol. 117: 1374-1376, 1996.
RESEARCH GROUP MEMBERS:
-
Maselli Maria Antonietta, R..O.
-
Piepoli Anna Lodadea, B.
-
Montanaro Simone, T.
AFFILIATION:
Laboratorio di Fisiopatologia Sperimentale
IRCCS. "Saverio de Bellis"
ADDRESS: Via Francesco Valente 4
CITY: Castellana Grotte (Bari)
POSTAL CODE: 70013
TELEPHONE: 080-4960231
FAX: 080-4960231/4961394
PUBLICATIONS:
-
RIEZZO G., PEZZOLLA F., MASELLI M.A., GIORGIO I. Electrical activity recorded
from the abdominal surface before and after right hemicolectomy in man.
Digestion 55: 185-190, 1994.
-
MASELLI M.A., CAROPPO R., DEBELLIS L., CURCI S., GIORGIO I. Effect of
trimipramina and fluoxetine on H+ secretion and transephitelial electrical
parameters of gastric mucosa. Med. Sci. Res. 22 : 263-266, 1994.
-
CHILOIRO M., PEZZOLLA F., RIEZZO G., MASELLI M.A., LORUSSO D. Gallbladder
motility before and after Billroth II gastric resection. Neurogastroenterology
and Motility 7: 145-149, 1995.
-
MASELLI M.A., PEZZOLLA F. PIEPOLI A.L., CARUSO M.L., LORUSSO D. Gallbladder
motility in vitro in man with gallstones following Billroth II gastric
resection. Neurogastroenterology and Motility 8: 29-33, 1996.
RESEARCH GROUP MEMBERS:
-
Soldani Giulio, P.O.
-
Mengozzi Grazia, R.U.
-
Intorre Luigi, R.U.
-
Bertini Simone, D.DR.
-
Della Croce Clara Maria, D.DR.
-
Luchetti Elena, D.DR.
-
Demi Sergio, T.L.
AFFILIATION:
Laboratorio di Farmacologia e Tossicologia
Istituto di Clinica Medica Veterinaria
Facoltą di Medicina Veterinaria
Universitą di Pisa
ADDRESS: Via Piagge, 2
CITY: Pisa
POSTAL CODE: 56124
TELEPHONE: 050 - 570583 - 570582 - 570525
FAX: 050 - 570771
PUBLICATIONS:
-
SOLDANI G., MENGOZZI G., INTORRE L., DE GIORGI G., CORUZZI G. AND BERTACCINI
G. Histamine H3 receptor- mediated inhibition of gastric acid secretion in
conscious dogs. Naunyn-Schmied. Arch. Pharmacol. 347: 61-65, 1993.
-
INTORRE L., MENGOZZI G., VANNI E., GRASSI F. AND SOLDANI G. The role of
peripheral opioid receptor subtypes in the modulation of gastric acid secretion
and plasma gastrin in dogs. Eur. J. Pharmacol. 243: 265-272, 1993.
-
MAUGERI S., FERRE' J.P., INTORRE L. AND SOLDANI G. Effects of medetomidine
on intestinal and colonic motility in the dog. J. vet. Pharmacol.
Therap. 17: 148-154, 1994.
-
SOLDANI G., INTORRE L., BERTINI S., LUCHETTI E., CORUZZI G. AND BERTACCINI
G. Regulation of gastric acid secretion by histamine H3 receptors in the
dog: an investigation into the site of action. Naunyn-Schmied- Arch.
Pharmacol. 350: 218-223, 1994.
-
INTORRE L., BLANDIZZI C., NATALE G., INTORRE D., MENGOZZI G. AND SOLDANI
G. Regulation of gastrin release in the dog by alfa2-adrenergic receptors.
J. Auton. Pharmacol. 14: 345-353, 1994.
-
INTORRE L., FORNAI F., ALESSANDRI' M.G., LENZI L., CORSINI G.U. AND
SOLDANI G. Behavioural and biochemical effects of the tremorgenic mycotoxin
verruculogen. Toxicol. Environ. Chem. 46: 119-125, 1994.
-
INTORRE L., MENGOZZI G., MACCHERONI M., BERTINI S. AND SOLDANI G.
Enrofloxacin-theophylline interaction: influence of enrofloxacin on theophylline
steady-state pharmacokinetics in the beagle dog. J. Vet. Pharmacol.
Therap. 18: 352-356, 1995.
-
MENGOZZI G., INTORRE L., BERTINI S. AND SOLDANI G. Pharmacokinetics of
enrofloxacin and its metabolite ciprofloxacin after intravenous and intramuscular
administration in sheep. Amer. J. Vet. Res. 57: 1040-1043, 1996.
-
INTORRE L., BERTINI S., LUCHETTI E., MENGOZZI G., CREMA F. AND SOLDANI G.
The effect of ethanol, beer and wine on histamine release from the dog stomach.
Alcohol. 13: 321- 326, 1996.
-
SOLDANI G., GARBARG M., INTORRE L., BERTINI S., ROULEAU A. AND SCHWARTZ J-C.
Modulation of entagastrin-induced histamine release by histamine H3 receptors
in the dog. Scand. J. Gastroenterol. 31: 631-638, 1996.
RESEARCH GROUP MEMBERS:
-
Tonini Marcello, P.A.
-
DíAgostino Gianluigi, R.U.
-
Di Nucci Amalia, R.U.
-
Ricotti Paola, B.
-
Tagliani Monica, B.
AFFILIATION :
Sezione di Farmacologia e Tossicologia,
Dipartimento di Medicina Interna e Terapia Medica
Facoltą di Medicina e Chirurgia
Universitą di Pavia
ADDRESS: Piazza Botta, 10
CITY: Pavia
POSTAL CODE: 27100
TELEPHONE: 0382-506363
FAX: 0382-22741
E-MAIL: tonini@ipv36.unipv.it
PUBLICATIONS :
-
COCCINI T., CANDURA S.M., MANZO L., COSTA L.G., TONINI M. Interaction of
the neurotoxic pesticides ivermectin and lindane with the enteric GABAA
receptor-ionophore complex in the guinea-pig. Eur. J. Pharmacol. (Environ.
Pharmacol. Toxicol. Section), 248 : 1-6, 1993.
-
WATERMAN S.A., COSTA M., TONINI M. Accommodation mediated by enteric inhibitory
reflexes in the isolated guinea-pig small intestine. J. Physiol.,
474 : 539-546, 1994.
-
TONINI M., MESSORI E., FRANCESCHETTI G.P., RIZZI C.A., CASTOLDI A.F., COCCINI
T., CANDURA S.M. Characterization of the 5-hydroxytryptamine receptor
potentiating neuromuscular cholinergic transmission in strips of human isolated
detrusor muscle. Brit. J. Pharmacol., 113 : 1-2, 1994.
-
CICCOCIOPPO R., ONORI L., MESSORI E., CANDURA S.M., COCCINI T., TONINI M.
Role of nitric oxide-dependent and -independent mechanisms in peristalsis
and accommodation in the rabbit distal colon. J. Pharmacol. Exp. Ther.,
270 : 929-937, 1994.
-
WATERMAN S.A., TONINI M., COSTA M. The role of ascending excitatory and
descending inhibitory pathways in peristalsis in the isolated guinea-pig
small intestine. J. Physiol., 481 : 223-232, 1994.
-
LUCCHELLI A., SANTAGOSTINO-BARBONE M.G., BARBIERI A., CANDURA S.M., TONINI
M. The interaction of antidepressant drugs with central and peripheral (enteric)
5-HT3 and 5-HT4 receptors. Brit. J. Pharmacol., 114 : 1017-1025
1995.
-
MESSORI E., CANDURA S.M., COCCINI T., BALESTRA B., TONINI M. 5-HT3 receptor
involvement in descending reflex relaxation in the rabbit isolated distal
colon. Eur. J. Pharmacol., 286 : 205-208, 1995.
-
TONINI M., BROOKES S.J.H, HUMPHREYS C.M.S., COSTA M. Dissociation of the
ascending excitatory reflex from peristalsis in the guinea-pig small
intestine. Neuroscience , 73 : 287-297, 1996.
-
CANDURA S.M., MESSORI E., FRANCESCHETTI G.P., D'AGOSTINO G., VICINI D., TONINI
M. Neural 5-HT4 receptors in the human isolated detrusor muscle: effects
of indole, benzimidazolone and substituted benzamide agonists and
antagonists. Brit. J. Pharmacol., 118 : 1965-1970, 1996.
Torna al sommario